Sign in →

Test Code STRNG Strongyloides Antibody, IgG, Serum

Useful For

Screening for the presence of IgG-class antibodies to Strongyloides

 

This test is not useful for monitoring patient response to therapy as IgG-class antibodies to Strongyloides may remain detectable following resolution of infection.

Reporting Name

Strongyloides Ab, IgG, S

Specimen Type

Serum


Specimen Required


Collection Container/Tube:

Preferred: Serum gel

Acceptable: Red top

Submission Container/Tube: Plastic vial

Specimen Volume: 0.5 mL

Collection Instructions: Centrifuge and aliquot serum into a plastic vial.


Specimen Minimum Volume

0.4 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Serum Refrigerated (preferred) 30 days
  Frozen  30 days

Reject Due To

Gross hemolysis Reject
Gross lipemia Reject
Gross icterus Reject
Heat inactivated specimen Reject

Reference Values

Negative

Reference values apply to all ages.

Supportive Data

Accuracy:

The Bordier Strongyloides enzyme immunoassay was compared to the Strongyloides luciferase immunoprecipitation (LIPS) assay as performed at the National Institutes of Health and to the SciMedix Strongyloides IgG enzyme-linked immunosorbent assay using 102 serum samples. Based on prior publications, the LIPS assay was considered the gold standard comparator for this evaluation.(1,2) The comparative data is shown below in Tables 1, 2, and 3:

 

Table 1. Comparison of results between the Bordier and NIH LIPS assays (n=102)

 

NIH LIPS

Positive

Negative

Bordier

Positive

51

12

Negative

3

36

 

 

 

 

 

 

 

 

Positive Agreement: 96.2% (51/53); 95% CI: 86.5%-99.7%

Negative Agreement: 75.0% (36/48); 95% CI: 61.1%-85.2%

Overall Agreement: 85.3% (87/102); 95% CI: 77.0%-91.0%

 

Table 2. Comparison of results between the Bordier and SciMedx assays (n=102)

SciMedx

Positive

Negative

Equivocal

Bordier

Positive

45

13

5

Negative

8

30

1

 

 

 

 

 

 

 

 

Positive Agreement: 84.9% (45/53); 95% CI: 72.7%-92.4%

Negative Agreement: 69.8% (30/43); 95% CI: 54.8%-81.5%

Overall Agreement: 73.5% (75/102); 95% CI: 64.2%-81.2%

 

Table 3. Comparison of results between the SciMedx and NIH LIPS assays (n=102)

NIH LIPS

Positive

Negative

SciMedix

Positive

42

11

Negative

7

36

Equivocal*

5

1

 

 

 

 

 

 

 

 

 

*Equivocal results were excluded from calculation of positive and negative agreement.

 

Positive Agreement: 85.7% (42/49); 95% CI: 73.0%-93.2%

Negative Agreement: 76.6% (36/47); 95% CI: 62.6%-86.6%

Overall Agreement: 76.5% (78/102); 95% CI: 67.3%-83.7%

 

Reference Range:

Evaluation was performed on 100 normal donor serum samples by the Bordier Strongyloides assay and 99% (99/100) were negative.

Day(s) Performed

Monday, Wednesday, Thursday, Friday

Report Available

Same day/1 to 4 days

Specimen Retention Time

14 days

Performing Laboratory

Mayo Clinic Laboratories in Rochester

CPT Code Information

86682

LOINC Code Information

Test ID Test Order Name Order LOINC Value
STRNG Strongyloides Ab, IgG, S 34376-4

 

Result ID Test Result Name Result LOINC Value
STRNG Strongyloides Ab, IgG, S 80660-4

Testing Algorithm

For more information see Parasitic Investigation of Stool Specimens Algorithm.

Forms

If not ordering electronically, complete, print, and send Infectious Disease Serology Test Request (T916) with the specimen.