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HelpTest Code QNADL Adalimumab Quantitative, Serum
Specimen Required
Only orderable as part of profile. For more information see ADALP / Adalimumab Quantitative with Antibody, Serum.
Patient Preparation: For 12 hours before specimen collection, patient should not take multivitamins or dietary supplements (eg, hair, skin, and nail supplements) containing biotin (vitamin B7).
Collection Container/Tube:
Supplies: Sarstedt Aliquot Tube, 5 mL (T914)
Preferred: Serum gel
Acceptable: Red top
Submission Container/Tube: Plastic vial
Specimen Volume: 0.4 mL Serum
Collection Instructions:
1. Draw blood immediately before the next dose of drug administration (trough specimen).
2. Centrifuge and aliquot serum into a plastic vial.
Useful For
Therapeutic drug monitoring of adalimumab
Quantifying adalimumab as part of a profile evaluating patients for loss of response, partial response on initiation of therapy, autoimmune or hypersensitivity reactions, primary nonresponse, reintroduction after drug holiday, endoscopic/computed tomography enterography recurrence (in inflammatory bowel disease), acute infusion reactions and proactive monitoring
This test does not differentiate between the originator and biosimilar products.
Reporting Name
Adalimumab QN, SSpecimen Type
SerumSpecimen Minimum Volume
See Specimen Required
Specimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Serum | Refrigerated (preferred) | 28 days |
| Frozen | 28 days |
Reject Due To
| Gross hemolysis | OK |
| Gross lipemia | OK |
| Heat-treated | Reject |
| Gross icterus | OK |
Reference Values
Only orderable as part of profile. For more information see ADALP / Adalimumab Quantitative with Antibody, Serum.
Limit of quantitation is 0.8 mcg/mL. Optimal therapeutic ranges are disease specific.
Day(s) Performed
Monday, Wednesday, Friday
Report Available
2 to 4 daysSpecimen Retention Time
14 daysPerforming Laboratory
Mayo Clinic Laboratories in Rochester
CPT Code Information
80145
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| QNADL | Adalimumab QN, S | 86894-3 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| QNADL | Adalimumab QN, S | 86894-3 |
Testing Algorithm
For information see Ulcerative Colitis and Crohn Disease Therapeutic Drug Monitoring Algorithm.