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HelpTest Code MECPI Methicillin Resistance Gene, Molecular Detection, PCR, Varies
Infectious
Shipping Instructions
1. For shipping information, see Infectious Specimen Shipping Guidelines.
2. Place specimen in a large infectious container and label as an etiologic agent/infectious substance.
Necessary Information
Organism identification and specimen source are required.
Specimen Required
Supplies: Infectious Container, Large (T146)
Container/Tube: Agar slant or other appropriate media
Specimen Volume: Organism in pure culture
Collection Instructions:
1. Perform isolation of bacteria.
2. Organism must be in pure culture, actively growing. Do not submit mixed cultures.
Useful For
Detecting mecA in staphylococcal bacterial isolates
Evaluating treatment options when oxacillin or cefoxitin breakpoints are unavailable (eg, certain Staphylococcus species other than Staphylococcus aureus)
Predicting antimicrobial resistance when bacterial growth is inadequate for phenotypic antimicrobial susceptibility testing (eg, staphylococcal small colony variants)
Assessing discrepancies amongst cefoxitin and oxacillin phenotypic testing results or penicillin-binding protein 2a test results
Special Instructions
Reporting Name
Methicillin Resistance Gene, VariesSpecimen Type
VariesSpecimen Minimum Volume
See Specimen Required
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Varies | Ambient (preferred) | ||
| Refrigerated | |||
Reject Due To
| Agar plate Mixed culture |
Reject |
Reference Values
Not detected
Supportive Data
Staphylococcal bacterial isolates were tested for the presence of mecA by the Cepheid GeneXpert - Xpert SA Nasal Complete compared to Mayo Clinic’s laboratory developed test (LDT) MARP / mecA, Molecular Detection, PCR, Varies. There was 95% or greater concordance for the detection of 25 mecA negative methicillin susceptible Staphylococcus species other than Staphylococcus aureus, 10 mecA negative methicillin susceptible S aureus, and 20 mecA positive methicillin-resistant S aureus. Greater than 95% concordance was achieved for 25 mecA positive methicillin-resistant Staphylococcus species other than S aureus isolates. Additionally, 10 isolates of Staphylococcus saccharolyticus and 10 isolates of small colony variant staphylococci were tested for the presence of mecA by both the Cepheid GeneXpert - Xpert SA Nasal Complete platform and the LDT, yielding 95% or greater correlation.
Day(s) Performed
Monday through Friday
Report Available
2 to 4 daysSpecimen Retention Time
30 daysPerforming Laboratory
Mayo Clinic Laboratories in Rochester
CPT Code Information
87641
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| MECPI | Methicillin Resistance Gene, Varies | 48813-0 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| MECPR | mecA Resistance Gene | 48813-0 |
| MEORG | Organism Identified by Client | In Process |
| MESCR | Specimen Source | 31208-2 |