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Test Code LAB868 Hepatitis C Antibody Screen W/ Reflex HCV RNA PCR

Performing Laboratory

Asante Rogue Regional Medical Center

Specimen Minimum Volume

0.5 mL

Billing Code

3020045

Methodology

Chemiluminescence (CLIA)

Specimen Requirements

Yellow (Gold) top tube (SST)

Plain Red top tube  

 

Cord blood is NOT to be used 

Day(s) Test Set Up

Tests are performed Monday through Friday.


Positive results are called to physician

 

Positive results also require public health reporting and follow-up. See Additional Information

 

Postive results are sent to Mayo for comfirmation testing.

Test Classification and CPT Coding

86803  -  Hepatitis C antibody

Additional Information

Screening test for antibodies to Hepatitis C virus.  Formally classified as a type of Non A, Non B Hepatitis.  Often associated with post-transfusion hepatitis.  This type of hepatitis is also seen in IV drug users or health care workers.  Hepatitis C is transmitted through the exposure of blood and body fluids.

 

Total Antibody Assay.  A positive antibody response does not distinguish between acute or remote exposure.  Antibody response to the Hepatitis C virus may be delayed.  Repeat assay over 6 to 12 months may detect delayed seroconversion.


Per CDC guidelines, strongly positive samples (cut-off value < 11.0) are reported directly as “strongly positive.”  Weaker positive samples (cut-off value < 11.0) are reported as “unconfirmed positive.” 

Samples with a cut-off value of <<11.0 require confirmation by Hepatitis C RNA (HCVQN)

The HCVQN assay will be immediately sent to a reference laboratory if indicated.


Reflex Testing: HCVQN

Specimen Transport Temperature and Stability

Centrifuge refrigerate within 2 hours of collection 

Serum stable 7 days refrigerated at 2° to 8° C

Freeze for longer storage

Performing Department

Chemistry

Reasons for Rejection

Icterus

Lipemia

Hemolysis

Quantity not sufficient (QNS)

Lack of Two Patient Identifiers:

         1-Patient's First & Last name 

         2-Patient's Date of Birth