Test Code LAB836 Acetylcholine Receptor (Muscle AChR) Binding Antibody, Serum
Performing Laboratory
Mayo Clinic Laboratories in RochesterReporting Name
ACh Receptor (Muscle) Binding AbSpecimen Type
SerumOrdering Guidance
Standalone testing (this test) is recommended in certain situations.
This test should not be requested in patients who have recently received radioisotopes, therapeutically or diagnostically, because of potential assay interference. The specific waiting period before specimen collection will depend on the isotope administered, the dose given, and the clearance rate in the individual patient. Specimens will be screened for radioactivity prior to analysis. Radioactive specimens received in the laboratory will be held for 1 week and assayed if sufficiently decayed or canceled if radioactivity remains.
Specimen Required
Patient Preparation: For optimal antibody detection, specimen collection is recommended prior to initiation of immunosuppressant medication.
Supplies: Sarstedt Aliquot Tube 5 mL (T914)
Collection Container/Tube:
Preferred: Red top
Acceptable: Serum gel
Submission Container/Tube: Plastic vial
Specimen Volume: 1.5 mL
Reject Due To
Gross hemolysis | Reject |
Gross lipemia | Reject |
Gross icterus | Reject |
Specimen Stability Information
Specimen Type | Temperature | Time | Special Container |
---|---|---|---|
Serum | Refrigerated (preferred) | 28 days | |
Frozen | 28 days | ||
Ambient | 72 hours |
Specimen Minimum Volume
1 mL
Day(s) Performed
Monday through Sunday
Specimen Retention Time
28 daysReport Available
3 to 6 daysReference Values
≤0.02 nmol/L
Useful For
Supporting the diagnosis of autoimmune myasthenia gravis (MG) in adults and children
Distinguishing autoimmune from congenital MG in adults and children or other acquired forms of neuromuscular junction transmission disorders
An adjunct to the test for P/Q-type calcium channel binding antibodies as a diagnostic aid for Lambert-Eaton myasthenic syndrome
Testing Algorithm
This is the primary diagnostic test for myasthenia gravis.
CPT Code Information
86041
LOINC Code Information
Test ID | Test Order Name | Order LOINC Value |
---|---|---|
ARBI | ACh Receptor (Muscle) Binding Ab | 97558-1 |
Result ID | Test Result Name | Result LOINC Value |
---|---|---|
8338 | ACh Receptor (Muscle) Binding Ab | 97558-1 |
Forms
If not ordering electronically, complete, print, and send a Neurology Specialty Testing Client Test Request (T732) with the specimen.