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Test Code LAB741 Alkaline Phosphatase, Total and Isoenzymes, Serum

Important Note

Mayo test code: ALKI

Differentiating between Bone and Liver (For Bone only order Mayo test BAP)

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Reporting Name

Alkaline Phosphatase, Tot and Iso,S

Specimen Type

Serum


Necessary Information


Patient's age and sex are required.



Specimen Required


Collection Container/Tube:

Preferred: Serum gel

Acceptable: Red top

Submission Container/Tube: Plastic vial

Specimen Volume: 1 mL, divided

Collection Instructions: Centrifuge and aliquot serum into 2 tubes, each containing 0.5 mL


Reject Due To

Gross hemolysis Reject
Gross lipemia OK
Gross icterus OK

Specimen Stability Information

Specimen Type Temperature Time Special Container
Serum Frozen (preferred) 14 days
  Ambient  7 days
  Refrigerated  7 days

Specimen Minimum Volume

0.5 mL divided into 2 tubes each containing 0.25 mL

Day(s) Performed

Monday through Friday

Specimen Retention Time

7 days

Report Available

2 to 5 days

Reference Values

ALKALINE PHOSPHATASE

Males

0-14 days: 83-248 U/L

15 days-<1 year: 122-469 U/L

1-<10 years: 142-335 U/L

10-<13 years: 129-417 U/L

13-<15 years: 116-468 U/L

15-<17 years: 82-331 U/L

17-<19 years: 55-149 U/L

≥19 years: 40-129 U/L

Females

0-14 days: 83-248 U/L

15 days-<1 year: 122-469 U/L

1-<10 years: 142-335 U/L

10-<13 years: 129-417 U/L

13-<15 years: 57-254 U/L

15-<17 years: 50-117 U/L

≥17 years: 35-104 U/L

 

ALKALINE PHOSPHATASE ISOENZYMES

Liver 1%

0-6 years: 5.1-49.0%

7-9 years: 3.0-45.0%

10-13 years: 2.9-46.3%

14-15 years: 7.8-48.9%

16-18 years: 14.9-50.5%

≥19 years: 27.8-76.3%

Liver 1

0-6 years: 7.0-112.7 IU/L

7-9 years: 7.4-109.1 IU/L

10-13 years: 7.8-87.6 IU/L

14-15 years: 10.3-75.6 IU/L

16-18 years: 13.7-78.5 IU/L

≥19 years: 16.2-70.2 IU/L

Liver 2%

0-6 years: 2.9-13.7%

7-9 years: 3.7-12.5%

10-13 years: 2.9-22.3%

14-15 years: 2.2-19.8%

16-18 years: 1.9-12.5%

≥19 years: 0.0-8.0%

Liver 2

0-6 years: 3.0-41.5 IU/L

7-9 years: 4.0-35.6 IU/L

10-13 years: 3.3-37.8 IU/L

14-15 years: 2.2-32.1 IU/L

16-18 years: 1.4-19.7 IU/L

≥19 years: 0.0-5.8 IU/L

Bone %

0-6 years: 41.5-82.7%

7-9 years: 39.9-85.8%

10-13 years: 31.8-91.1%

14-15 years: 30.6-85.4%

16-18 years: 38.9-72.6%

≥19 years: 19.1-67.7%

Bone

0-6 years: 43.5-208.1 IU/L

7-9 years: 41.0-258.3 IU/L

10-13 years: 39.4-346.1 IU/L

14-15 years: 36.4-320.5 IU/L

16-18 years: 32.7-214.6 IU/L

≥19 years: 12.1-42.7 IU/L

Intestine %

0-6 years: 0.0-18.4%

7-9 years: 0.0-18.3%

10-13 years: 0.0-11.8%

14-15 years: 0.0-8.2%

16-18 years: 0.0-8.7%

≥19 years: 0.0-20.6%

Intestine

0-6 years: 0.0-37.7 IU/L

7-9 years: 0.0-45.6 IU/L

10-13 years: 0.0-40.0 IU/L

14-15 years: 0.0-26.4 IU/L

16-18 years: 0.0-12.7 IU/L

≥19 years: 0.0-11.0 IU/L

Placental

Not present

Useful For

Diagnosis and treatment of liver, bone, intestinal, and parathyroid diseases

 

Determining the tissue source of increased alkaline phosphatase (ALP) activity in serum

 

Differentiating between liver and bone sources of elevated ALP

CPT Code Information

84075

84080

LOINC Code Information

Test ID Test Order Name Order LOINC Value
ALKI Alkaline Phosphatase, Tot and Iso,S 24332-9

 

Result ID Test Result Name Result LOINC Value
ALP Alkaline Phosphatase, S 6768-6
89503 Alkaline Phosphatase Isoenzymes, S 49243-9
45488 Liver 1 % 15348-6
57034 Liver 1 13874-3
45489 Liver 2 % 15349-4
57035 Liver 2 13875-0
45490 Bone % 15013-6
57036 Bone 1777-2
45491 Intestine % 15014-4
57037 Intestine 1778-0
29324 Placental 40793-2

Profile Information

Test ID Reporting Name Available Separately Always Performed
ALP Alkaline Phosphatase, S Yes Yes
ALKE Alkaline Phosphatase Isoenzymes, S No Yes