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HelpTest Code LAB524 DHEAS-Sulfate
Performing Laboratory
Asante Rogue Regional Medical Center
Specimen Minimum Volume
0.5 mL
Billing Code
2053221
Methodology
Chemiluminescence (CLIA)
Day(s) Test Set Up
Monday through Sunday
Test Classification and CPT Coding
82627 - Dehydroepiandrosterone-sulfate (DHEA-S)
Additional Information
DHEA-S may be used in the differential diagnosis of
Cushing’s syndrome. DHEA-S may also be used to evaluate
adrenocortical diseases, such as congenital adrenal hyperplasia and
adrenal tumors. In hirsute female patients, increased DHEA-S
levels have been associated with virilizing adrenal tumors.
Patients with polycystic ovary syndrome have often demonstrated
elevated levels of DHEA-S, suggesting an adrenal androgen
contribution to the defect in this disorder.
DHEA-S dietary supplements have been suggested to reverse certain
effects of aging in both men and women, although this
supplementation has not been without controversy. After age
30, there is a gradual decrease in DHEA-S. By age 70-80,
DHEA-S values are ~ 10%-25% of their peak values. A
cross-sectional analysis of older adults has found that men with
DHEA-S levels in the highest quartile are more fit, lean, and have
higher levels of total and free testosterone than do comparable men
with DHEA-S levels in the lowest quartile.
No comparable correlation was found in women
Specimen Transport Temperature and Stability
Centrifuge and refrigerate within 2 hours of collection
Primary tube: Spun SST stable 24 hours at 2° to 8° C
Serum stable 48 hours if aliquoted and refrigerated at 2° to 8° C
Freeze if testing is delayed
Performing Department
Chemistry
Reasons for Rejection
Hemolysis
Quantity not sufficient (QNS)
Lack of Two Patient Identifiers:
1-Patient's First & Last name
2-Patient's Date of Birth