Test Code LAB50 Bilirubin, Total
Useful For
Causes of high bilirubin: Liver disease, hepatitis, cholangitis, cirrhosis, other types of liver disease (including primary or secondary neoplasia); alcoholism (usually with high AST, GGT, MCV or some combination of these findings); biliary obstruction (intrahepatic, extrahepatic); infectious mononucleosis (look also for increased LDH, lymphocytosis). Gilbert’s disease (familial hyperbilirubinemia) is encountered as a moderate elevation with otherwise unremarkable chemistries. Dubin-Johnson Syndrome, Crigler-Najar Syndrome and Fructose
Intolerance. Anorexia or prolonged fasting: 36 hours or more may cause moderate rise. Pernicious anemia, hemolytic anemias, erythroblastosis fetalis, other neonatal jaundice, hematoma.
Drugs: A large number of drugs can cause jaundice by in vivo action or by chemistry methodology. Drugs causing cholestasis and/or hepatocellular damage include diphenylhydantoin, azathioprine, phenothiazines, erythromycin, penicillin, sulfonamides, oral contraceptives, anabolic-androgenic steroids, halothane, aminosalicylic acid, isoniazid, methyldopa, indomethacin and pyrazinamide.
Performing Laboratory
Asante Rogue Regional Medical Center (ARRMC)/ Asante Three Rivers Medical Center (ATRMC)/ Asante Ashland Community Hospital (AACH)/ Asante White City Laboratory
Performing Department
Chemistry
Specimen Required
Lithium Heparin Green top tube
Infants Only: 1 full Green or Yellow microtainer
Specimen Minimum Volume
0.5 mL
Specimen Stability Information
Protect from light; Exposure will decrease results
Centrifuge and refrigerate within 2 hours of collection
When well protected from light, bilirubin in serum or plasma is stable for 3 days at 2° to 8° C
Reject Due To
Newborns only: Microtainer samples should be protected from light using either an amber colored microtainer or other light protection means. If unprotected, microtainers are only stable for 1 hour from time of draw.
Hemolysis
Quantity not sufficient (QNS)
Lack of Two Patient Identifiers:
1-Patient's First & Last name
2-Patient's Date of Birth
Day(s) Performed
Routine – same day
ASAP – 2 hours after receipt of specimen in lab
STAT – 1 hour after receipt of specimen in lab
Method Name
Diazo Reaction
CPT Code Information
82247
Bilirubin; total
Billing Code
2050151
Reference Values
BILIRUBIN TOTAL AND DIRECT | Bilirubin Total | 0 up to 2 Days | 3.4 - 11.5 mg/dL |
2 Days up to 5 Days | 1.5 - 12.0 mg/dL | ||
5 Days up to 19 Years | 0.6 - 1.4 mg/dL | ||
19 years and up | 0.3 - 1.2 mg/dL | ||
Bilirubin Direct | 0 up to 1 Month | ≤ 0.6 mg/dL | |
1 Month and Up | ≤ 0.2 mg/dL |
Secondary ID
Total Bilirubin
Conjugated and Unconjugated Bilirubin