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Test Code LAB50 Bilirubin, Total

Useful For

Causes of high bilirubin:  Liver disease, hepatitis, cholangitis, cirrhosis, other types of liver disease (including primary or secondary neoplasia); alcoholism (usually with high AST, GGT, MCV or some combination of these findings); biliary obstruction (intrahepatic, extrahepatic); infectious mononucleosis (look also for increased LDH, lymphocytosis).  Gilbert’s disease (familial hyperbilirubinemia) is encountered as a moderate elevation with otherwise unremarkable chemistries.  Dubin-Johnson Syndrome, Crigler-Najar Syndrome and Fructose
Intolerance. Anorexia or prolonged fasting:  36 hours or more may cause moderate rise.  Pernicious anemia, hemolytic anemias, erythroblastosis fetalis, other neonatal jaundice, hematoma.


Drugs:  A large number of drugs can cause jaundice by in vivo action or by chemistry methodology.  Drugs causing cholestasis and/or hepatocellular damage include diphenylhydantoin, azathioprine, phenothiazines, erythromycin, penicillin, sulfonamides, oral contraceptives, anabolic-androgenic steroids, halothane, aminosalicylic acid, isoniazid, methyldopa, indomethacin and pyrazinamide.

Performing Laboratory

Asante Rogue Regional Medical Center (ARRMC)/ Asante Three Rivers Medical Center (ATRMC)/ Asante Ashland Community Hospital (AACH)/ Asante White City Laboratory

 

Performing Department

Chemistry

Specimen Minimum Volume

0.5 mL

Specimen Stability Information

Protect from light;  Exposure will decrease results

Centrifuge and refrigerate within 2 hours of collection
When well protected from light, bilirubin in serum or plasma is stable for 3 days at 2° to 8° C

Reject Due To

Newborns only: Microtainer samples should be protected from light using either an amber colored microtainer or other light protection means. If unprotected, microtainers are only stable for 1 hour from time of draw.

 

Hemolysis

Quantity not sufficient (QNS)

Lack of Two Patient Identifiers:

         1-Patient's First & Last name 

         2-Patient's Date of Birth

Day(s) Performed

Routine – same day

ASAP – 2 hours after receipt of specimen in lab

STAT – 1 hour after receipt of specimen in lab

Method Name

Diazo Reaction

CPT Code Information

82247
Bilirubin; total 

Billing Code

2050151

Reference Values

 

BILIRUBIN TOTAL AND DIRECT Bilirubin Total 0 up to 2 Days 3.4 - 11.5 mg/dL
2 Days up to 5 Days 1.5 - 12.0 mg/dL
5 Days up to 19 Years 0.6 - 1.4 mg/dL
19 years and up 0.3 - 1.2 mg/dL
Bilirubin Direct 0 up to 1 Month ≤ 0.6 mg/dL
1 Month and Up ≤ 0.2 mg/dL

Secondary ID

Total Bilirubin
Conjugated and Unconjugated Bilirubin