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HelpTest Code LAB467 Cytomegalovirus (CMV) Antibodies, IgG, Serum
Performing Laboratory
Mayo Clinic Laboratories in Rochester
Reporting Name
Cytomegalovirus Ab, IgG, SSpecimen Type
SerumSpecimen Required
Collection Container/Tube:
Preferred: Serum gel
Acceptable: Red top
Submission Container/Tube: Plastic vial
Specimen Volume: 0.5 mL
Collection Instructions: Centrifuge and aliquot serum into a plastic vial.
Reject Due To
| Gross hemolysis | Reject |
| Gross lipemia | Reject |
| Gross icterus | Reject |
| Heat-inactivated specimen | Reject |
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Serum | Refrigerated (preferred) | 14 days | |
| Frozen | 14 days |
Specimen Minimum Volume
0.4 mL
Day(s) Performed
Monday through Saturday
Specimen Retention Time
14 daysReport Available
Same day/1 to 3 daysReference Values
Negative (reported as positive, negative, or equivocal)
Useful For
Determining whether a patient (especially transplant recipients and organ and blood donors) has had a recent infection or previous exposure to cytomegalovirus
CPT Code Information
86644
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| CMVG | Cytomegalovirus Ab, IgG, S | 13949-3 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| CMVG | Cytomegalovirus Ab, IgG, S | 13949-3 |
Supportive Data
To evaluate the accuracy of the BioPlex cytomegalovirus (CMV) IgG multiplex flow immunoassay, 598 prospective serum samples submitted for routine CMV IgG testing by the VIDAS enzyme-linked fluorescence immunoassay (ELFA; bioMerieux) were also analyzed in a blinded fashion by the BioPlex assay within a 24-hour period. Samples with discordant results after initial testing were repeated by both assays during the same freeze/thaw cycle. Further resolution of discrepant results was performed by using the Diamedix CMV IgG enzyme immunoassay. The results are summarized in the table below:
Table. CMV IgG Comparison
|
|
CMV IgG (VIDAS ELFA) |
|||
|
BioPlex CMV IgG |
|
Positive |
Negative |
Equivocal |
|
Positive |
336 |
2(a) |
0 |
|
|
Negative |
3(b) |
254 |
3 |
|
|
Equivocal |
0 |
0 |
0 |
|
a) Both serum samples were negative by the Diamedix CMV IgG EIA
b) All three serum samples were negative by the Diamedix CMB IgG EIA
Sensitivity: 99.1% (336/339); 95% CI: 97.3%-99.8%
Specificity: 99.2% (254/256); 95% CI: 97.0%-100%)
Overall Percent Agreement: 98.7% (590/598); 95% CI: 97.3%-99.4%
Forms
If not ordering electronically, complete, print, and send Infectious Disease Serology Test Request (T916) with the specimen.