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HelpTest Code LAB1231888 Measles (Rubeola) Virus Antibody, IgM and IgG, Serum
Performing Laboratory
Mayo Clinic Laboratories in Rochester
Reporting Name
Measles (Rubeola) Ab, IgM and IgG,SSpecimen Type
SerumSpecimen Required
Collection Container/Tube:
Preferred: Serum gel
Acceptable: Red top
Submission Container/Tube: Plastic vial
Specimen Volume: 1 mL
Collection Instructions: Centrifuge and aliquot serum into a plastic vial.
Reject Due To
| Gross hemolysis | Reject |
| Gross lipemia | Reject |
| Heat-inactivated specimen | Reject |
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Serum | Refrigerated (preferred) | 14 days | |
| Frozen | 14 days |
Specimen Minimum Volume
0.6 mL
Day(s) Performed
Monday through Saturday
Specimen Retention Time
14 daysReport Available
Same day/1 to 3 daysReference Values
IMMUNOGLOBULIN M
Negative
Reference values apply to all ages.
IMMUNOGLOBULIN G
Vaccinated: positive (≥1.1 AI)
Unvaccinated: negative (≤0.8 AI)
Reference values apply to all ages.
Useful For
Diagnosing measles virus infection
Determination of immune status of individuals to the measles virus using IgG antibody testing
Documentation of previous infection with measles virus in an individual without a previous record of immunization to measles virus
CPT Code Information
86765-Rubeola IgM
86765-Rubeola IgG
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| ROGM | Measles (Rubeola) Ab, IgM and IgG,S | 90253-6 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| 80979 | Measles (Rubeola) Ab, IgM, S | 35276-5 |
| ROG | Measles (Rubeola) Ab, IgG, S | 35275-7 |
| DEXG3 | Measles IgG Antibody Index | 5244-9 |
Profile Information
| Test ID | Reporting Name | Available Separately | Always Performed |
|---|---|---|---|
| ROM | Measles (Rubeola) Ab, IgM, S | Yes | Yes |
| ROPG | Measles (Rubeola) Ab, IgG, S | Yes | Yes |
Supportive Data
Immunoglobulin G:
To evaluate the accuracy of the BioPlex Measles IgG multiplex flow immunoassay (MFI), 500 prospective serum samples were analyzed in a blinded fashion by the Diamedix Measles IgG enzyme immunoassay (EIA) and the BioPlex Measles IgG assay. Samples with discordant results after initial testing were repeated by both assays during the same freeze/thaw cycle. Further discrepancies were evaluated by the SeraQuest Measles IgG EIA . The results are summarized in the table below:
Table: Diamedix measles IgG EIA
|
BioPlex measles IgG |
|
Positive |
Negative |
Equivocal |
|
Positive |
420 |
1(a) |
0 |
|
|
Negative |
10(b) |
27 |
17 |
|
|
Equivocal |
14 |
0 |
11 |
(a) This sample tested negative by the SeraQuest Measles IgG EIA
(b) All 10 samples tested positive by the SeraQuest Measles IgG EIA
Sensitivity: 94.6% (420/444); 95% CI: 92.1%-96.4%
Specificity: 96.4% (27/28); 95% CI: 80.8%-100.0%
Overall Percent Agreement: 91.6% (458/500); 95% CI: 88.8%-93.8%
Forms
If not ordering electronically, complete, print, and send Infectious Disease Serology Test Request (T916) with the specimen.