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HelpTest Code LAB1231887 Measles (Rubeola) Antibodies, IgG, Serum
Performing Laboratory
Mayo Clinic Laboratories in Rochester
Reporting Name
Measles (Rubeola) Ab, IgG, SSpecimen Type
SerumSpecimen Required
Collection Container/Tube:
Preferred: Serum gel
Acceptable: Red top
Submission Instructions: Plastic vial
Specimen Volume: 0.5 mL
Collection Instructions: Centrifuge and aliquot serum into a plastic vial.
Reject Due To
| Gross hemolysis | Reject |
| Gross lipemia | Reject |
| Gross icterus | Reject |
| Heat-inactivated specimen | Reject |
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Serum | Refrigerated (preferred) | 14 days | |
| Frozen | 14 days |
Specimen Minimum Volume
0.4 mL
Day(s) Performed
Monday through Saturday
Specimen Retention Time
14 daysReport Available
Same day/1 to 3 daysReference Values
Vaccinated: positive (≥1.1 AI)
Unvaccinated: negative (≤0.8 AI)
Reference values apply to all ages.
Useful For
Determining immune status of individuals to the measles virus
Documenting previous infection with measles virus in an individual without a previous record of immunization to measles virus
CPT Code Information
86765
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| ROPG | Measles (Rubeola) Ab, IgG, S | 77310-1 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| ROG | Measles (Rubeola) Ab, IgG, S | 35275-7 |
| DEXG3 | Measles IgG Antibody Index | 5244-9 |
Supportive Data
To evaluate the accuracy of the BioPlex Measles IgG multiplex flow immunoassay, 500 prospective serum specimens were analyzed in a blinded fashion by the Diamedix Measles IgG EIA (Diamedix) and the BioPlex Measles IgG assay. Specimens with discordant results after initial testing were repeated by both assays during the same freeze/thaw cycle. Further discrepancies were evaluated by the SeraQuest Measles IgG EIA (Quest International). The results are summarized in the table below.
Table. Comparison between Bioplex and Diamedix Measles Assays
|
|
Diamedix Measles IgG EIA |
|||
|
BioPlex Measles IgG |
|
Positive |
Negative |
Equivocal |
|
Positive |
420 |
1(a) |
0 |
|
|
Negative |
10(b) |
27 |
17 |
|
|
Equivocal |
14 |
0 |
11 |
|
(a) This sample tested negative by the SeraQuest Measles IgG EIA
(b) All 10 samples tested positive by the SeraQuest Measles IgG EIA
Sensitivity: 94.6% (420/444); 95% CI: 92.1% to 96.4%
Specificity: 96.4% (27/28); 95% CI: 80.8% to 100.0%
Overall Percent Agreement: 91.6% (458/500); 95% CI: 88.8% to 93.8%
Forms
If not ordering electronically, complete, print, and send Infectious Disease Serology Test Request (T916) with the specimen.