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HelpTest Code LAB1230160 JAK2 V617F Mutation Detection, Blood
Performing Laboratory
Mayo Clinic Laboratories in Rochester
Reporting Name
JAK2 V617F Mutation Detection, BSpecimen Type
Whole Blood EDTAShipping Instructions
Specimen must arrive within 7 days of collection.
Specimen Required
Container/Tube:
Preferred: Lavender top (EDTA)
Acceptable: Yellow top (ACD)
Specimen Volume: 4 mL
Collection Instructions:
1. Invert several times to mix blood.
2. Send whole blood specimen in original tube. Do not aliquot.
Reject Due To
| Gross hemolysis | Reject |
| Moderately to severely clotted | Reject |
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Whole Blood EDTA | Ambient (preferred) | 7 days | PURPLE OR PINK TOP/EDTA |
| Refrigerated | 7 days | PURPLE OR PINK TOP/EDTA |
Specimen Minimum Volume
1 mL
Special Instructions
Day(s) Performed
Monday through Saturday
Specimen Retention Time
Whole blood: 2 weeks; Extracted DNA: 3 monthsReport Available
2 to 5 daysReference Values
An interpretive report will be provided.
Useful For
Aiding in the distinction between a reactive blood cytosis and a chronic myeloproliferative disorder using peripheral blood specimens
Testing Algorithm
For more information see:
-Erythrocytosis Evaluation Testing Algorithm
-Myeloproliferative Neoplasm: A Diagnostic Approach to Peripheral Blood Evaluation
CPT Code Information
81270-JAK2 (Janus kinase 2) (eg, myeloproliferative disorder) gene analysis, p.Val617Phe (V617F) variant
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| JAK2B | JAK2 V617F Mutation Detection, B | 43399-5 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| 39722 | JAK2 Result | 53761-3 |
| 29590 | JAK2 V617F Mutation Detection, B | 43399-5 |
Supportive Data
Analytical sensitivity is determined at 0.06% (by dilution of a JAK2 V617F-positive cell line into a negative cell line DNA).
Forms
1. Hematopathology Patient Information (T676)
2. If not ordering electronically, complete, print, and send a Hematopathology/Cytogenetics Test Request (T726) with the specimen.