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Test Code GDS Gadolinium, Serum

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Reporting Name

Gadolinium, S

Specimen Type

Serum


Specimen Required


Patient Preparation: High concentrations of gadolinium and iodine are known to interfere with most metal tests. If either gadolinium- or iodine-containing contrast media has been administered, a specimen should not be collected for 96 hours.

Supplies: Metal Free Specimen Vial (T173)

Collection Container/Tube: Plain, royal blue-top Vacutainer plastic trace element blood collection tube

Submission Container/Tube: 7-mL Mayo metal-free, screw-capped, polypropylene vial

Specimen Volume: 0.3 mL

Collection Instructions:

1. Allow the specimen to clot for 30 minutes; then centrifuge the specimen to separate serum from the cellular fraction.

2. Remove the stopper. Carefully pour specimen into Mayo metal-free, screw-capped vial, avoiding transfer of the cellular components of blood. Do not insert a pipette into the serum to accomplish transfer, and do not ream the specimen with a wooden stick to assist with serum transfer.

3. See Metals Analysis Specimen Collection and Transport for complete instructions.


Reject Due To

Gross hemolysis OK
Gross lipemia OK
Gross icterus OK

Specimen Stability Information

Specimen Type Temperature Time Special Container
Serum Refrigerated (preferred) 28 days METAL FREE
  Ambient  28 days METAL FREE
  Frozen  28 days METAL FREE

Specimen Minimum Volume

0.2 mL

Day(s) Performed

Thursday

Specimen Retention Time

14 days

Report Available

2 to 8 days

Reference Values

<0.5 ng/mL

Useful For

Aiding in documenting previous exposure to gadolinium-based contrast agents using serum specimens

CPT Code Information

83018

LOINC Code Information

Test ID Test Order Name Order LOINC Value
GDS Gadolinium, S 80912-9

 

Result ID Test Result Name Result LOINC Value
29251 Gadolinium, S 80912-9

Supportive Data

A small number of patients studied at Mayo Clinic have demonstrated measurable (0.6-2.1 ng/mL) gadolinium in serum collected 30 days after gadolinium infusion, so some prolonged elimination is possible.

 

Serum gadolinium concentrations above the stated reference range may indicate prolonged elimination, residual gadolinium retention, or continuing environmental exposure. However, elevated serum gadolinium concentrations do not necessarily indicate toxicity.

Forms

If not ordering electronically, complete, print, and send a Renal Diagnostics Test Request (T830) with the specimen.