Home
HelpTest Code CRMWC Collapsin Response-Mediator Protein-5-IgG, Western Blot, Spinal Fluid
Useful For
Evaluation of cases of chorea, vision loss, cranial neuropathy and myelopathy
Reporting Name
CRMP-5-IgG Western Blot, CSFSpecimen Type
CSFOrdering Guidance
It is recommended an evaluation be ordered in conjunction with this testing if not previously performed. Multiple neurological phenotype-specific autoimmune/paraneoplastic evaluations are available. For more information as well as phenotype-specific testing options, see Autoimmune Neurology Test Ordering Guide.
Additional Testing Requirements
Shipping Instructions
Send specimen refrigerated.
Necessary Information
Provide the following information:
-Relevant clinical information
-Ordering healthcare professional name, phone number, mailing address, and e-mail address
Specimen Required
Container/Tube: Sterile vial
Specimen Volume: 3 mL
Specimen Minimum Volume
2 mL
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| CSF | Refrigerated (preferred) | 28 days | |
| Frozen | 28 days | ||
| Ambient | 72 hours |
Reject Due To
| Gross hemolysis | Reject |
| Gross lipemia | Reject |
| Gross icterus | Reject |
Reference Values
Negative
Supportive Data
In the Neuroimmunology Laboratory's current clinical service activity, the frequency of collapsin response-mediator protein-5 (CRMP-5)-IgG detection is approximately 2 per 1,000 sera tested, approximating that of the Purkinje cell cytoplasmic autoantibody-type 1 (PCA-1, or "anti-Yo"). A lung carcinoma was found in 77% of 116 patients, mostly limited small cell type; 6% had thymoma and 7% had miscellaneous neoplasms.
Day(s) Performed
Monday through Thursday
Report Available
5 to 10 daysSpecimen Retention Time
28 daysPerforming Laboratory
Mayo Clinic Laboratories in Rochester
CPT Code Information
84182
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| CRMWC | CRMP-5-IgG Western Blot, CSF | 53707-6 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| 21747 | CRMP-5-IgG Western Blot, CSF | 53707-6 |