Test Code COBRU Cobalt/Creatinine Ratio, Random, Urine
Ordering Guidance
Specimen Required
Supplies: Urine Tubes, 10 mL (T068)
Collection Container/Tube: Clean, plastic urine collection container
Submission Container/Tube: Plastic, 10-mL urine tube or clean, plastic aliquot container with no metal cap or glued insert
Specimen Volume: 3 mL
Collection Instructions:
1. Collect a random urine specimen.
2. See Metals Analysis Specimen Collection and Transport for complete instructions.
Useful For
Detecting cobalt exposure in a random urine collection
Monitoring metallic prosthetic implant wear
This test is not useful for assessment of vitamin B12 activity.
Profile Information
Test ID | Reporting Name | Available Separately | Always Performed |
---|---|---|---|
COBR | Cobalt/Creat Ratio, U | No | Yes |
CRETR | Creatinine, Random, U | No | Yes |
Special Instructions
Reporting Name
Cobalt/Creat Ratio, Random, USpecimen Type
UrineSpecimen Minimum Volume
2 mL
Specimen Stability Information
Specimen Type | Temperature | Time |
---|---|---|
Urine | Refrigerated (preferred) | 28 days |
Frozen | 28 days | |
Ambient | 14 days |
Reject Due To
All specimens will be evaluated at Mayo Clinic Laboratories for test suitability.Reference Values
COBALT:
0-17 years: Not established
>17 years: <1.7 mcg/g Cr
CREATININE:
≥18 years old: 16-326 mg/dL
Reference values have not been established for patients who are younger than 18 years.
Specimen Retention Time
14 daysPerforming Laboratory

CPT Code Information
83018
82570
LOINC Code Information
Test ID | Test Order Name | Order LOINC Value |
---|---|---|
COBRU | Cobalt/Creat Ratio, Random, U | 13468-4 |
Result ID | Test Result Name | Result LOINC Value |
---|---|---|
607272 | Cobalt/Creat Ratio, U | 13468-4 |
CRETR | Creatinine, Random, U | 2161-8 |
Day(s) Performed
Monday