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General Information

Mayo Clinic Laboratories

Test Code CERAM MI-Heart Ceramides, Plasma

Useful For

Evaluating the risk of major adverse cardiovascular events within the next 1 to 5 years

Reporting Name

MI-Heart Ceramides, P

Specimen Type

Plasma EDTA


Specimen Required


Patient Preparation: Patients should not be receiving Intralipid because it may cause false elevations in measured ceramides.

Collection Container/Tube: Lavender top (EDTA)

Submission Container/Tube: Plastic vial

Specimen Volume: 1 mL

Collection Instructions: Centrifuge, aliquot at least 1 mL of plasma into a plastic vial and freeze within 8 hours.


Specimen Minimum Volume

0.5 mL

Specimen Stability Information

Specimen Type Temperature Time
Plasma EDTA Frozen (preferred) 30 days
  Refrigerated  24 hours
  Ambient  8 hours

Reject Due To

Gross hemolysis Reject
Gross lipemia OK
Gross icterus OK

Reference Values

MI-Heart Ceramide Risk Score:

0-2 Lower risk

3-6 Moderate risk

7-9 Increased risk

10-12 Higher risk

Ceramide (16:0): 0.19-0.36 mcmol/L

Ceramide (18:0): 0.05-0.14 mcmol/L

Ceramide (24:1): 0.65-1.65 mcmol/L

Ceramide (16:0)/(24:0): <0.11

Ceramide (18:0)/(24:0): <0.05

Ceramide (24:1)/(24:0): <0.45

 

Reference values have not been established for patients who are less than 18 years of age.

 

Note: Ceramide (24:0) alone has not been independently associated with disease and will not be reported.

Day(s) Performed

Monday, Wednesday, Friday

Report Available

2 to 7 days

Specimen Retention Time

14 days

Performing Laboratory

Mayo Clinic Laboratories in Rochester

CPT Code Information

0119U

LOINC Code Information

Test ID Test Order Name Order LOINC Value
CERAM MI-Heart Ceramides, P 93883-7

 

Result ID Test Result Name Result LOINC Value
42434 MI-Heart Ceramide Risk Score 93876-1
42428 Ceramide (16:0) 93882-9
42429 Ceramide (18:0) 93881-1
42430 Ceramide (24:1) 93880-3
42431 Ceramide (16:0)/(24:0) ratio 93879-5
42432 Ceramide (18:0)/(24:0) ratio 93878-7
42433 Ceramide (24:1)/(24:0) ratio 93877-9

Forms

If not ordering electronically, complete, print, and send a Cardiovascular Test Request Form (T724) with the specimen.