Test Code CEASF Carcinoembryonic Antigen (CEA), Spinal Fluid
Performing Laboratory
Mayo Clinic Laboratories in Rochester
Reporting Name
Carcinoembryonic Ag (CEA), CSFSpecimen Type
CSFSpecimen Required
Collection Container/Tube: Sterile vial
Submission Container/Tube: 13 x 75-mm tube
Specimen Volume: 0.5 mL
Collection Instructions: Submit specimen from collection vial number 1.
Reject Due To
No specimen should be rejectedSpecimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| CSF | Refrigerated (preferred) | 14 days |
| Frozen | 90 days | |
| Ambient | 7 days |
Specimen Minimum Volume
0.4 mL
Day(s) Performed
Monday through Saturday
Specimen Retention Time
12 monthsReport Available
1 to 3 daysReference Values
<0.6 ng/mL
Tumor markers are not specific for malignancy, and values may vary by method.
Useful For
Detecting meningeal carcinomatosis and intradural or extradural infiltration
Differentiating brain parenchymal metastasis from adenocarcinoma or squamous-cell carcinoma
CPT Code Information
82378
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| CEASF | Carcinoembryonic Ag (CEA), CSF | 2037-0 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| CEASF | Carcinoembryonic Ag (CEA), CSF | 2037-0 |
Method Description
The Access carcinoembryonic antigen (CEA) assay is a 2-site immunoenzymatic sandwich assay using 2 mouse monoclonal anti-CEA antibodies (MAb) that react with different epitopes of CEA. A sample is added to a reaction vessel, along with the first anti-CEA MAb-alkaline phosphatase conjugate and the second anti-CEA MAb bound to paramagnetic particles. The incubation is followed by a magnetic separation and washing. The chemiluminescent substrate Lumi-Phos 530 is added to the vessel and light generated by the reaction is measured with a luminometer. The light production is proportional to the concentration of CEA in the sample. The amount of analyte in the sample is determined by means of a stored, multipoint calibrator curve.(Package insert: Access CEA, Beckman Coulter Inc; 2020)
Forms
If not ordering electronically, complete, print, and send an Oncology Test Request (T729) with the specimen.