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Test Code BILHA Schistosoma species Antibody, IgG, Serum

Useful For

Detection of antibodies to Schistosoma species

Reporting Name

Schistosoma Ab, IgG, S

Specimen Type

Serum


Specimen Required


Supplies: Sarstedt Aliquot Tube, 5 mL (T914)

Collection Container/Tube:

Preferred: Serum gel

Acceptable: Red top

Submission Container/Tube: Plastic vial

Specimen Volume: 1 mL

Collection Instructions: Centrifuge and aliquot serum into plastic vial.


Specimen Minimum Volume

0.5 mL

Specimen Stability Information

Specimen Type Temperature Time
Serum Refrigerated (preferred) 30 days
  Frozen  30 days

Reject Due To

Gross hemolysis Reject
Gross lipemia Reject
Heat inactivated Reject

Reference Values

Negative

Supportive Data

The Mayo Clinic Infectious Disease Serology laboratory evaluated the accuracy of the NovaTec Schistosoma mansoni IgG enzyme-linked immunosorbent assay (ELISA) (as performed in our laboratory) using 64 serum samples that were previously tested by a fluorescent microsphere immunoassay at Focus Diagnostics. A comparison of the results is shown in Table 1.

 

Table 1. Accuracy of the NovaTec Schistosoma IgG assay compared to the Focus (Quest) Diagnostics assay

n = 64

Focus (Quest) Diagnostics FMI

Positive

Negative

NovaTec ELISA

Positive

31

1

Negative

1

20

Equivocal

5

6

 

Positive agreement (95% CI): 83.8% (68.5-92.6%)

Negative agreement (95% CI): 96.3% (80.2-100%)

Overall agreement (95% CI): 89.1% (82.6-97%)

 

The Mayo Clinic Infectious Disease Serology laboratory also evaluated the analytic specificity of the NovaTec S mansoni IgG ELISA using 36 serum samples positive for antibodies to other helminth and protozoa. The results are shown in Table 2 below.

 

Table 2. Analytical specificity studies

Specimen

No. of specimens tested

No. of sera positive or equivocal by the S mansoni IgG ELISA

Entamoeba histolytica IgG Ab

6

0

Echinococcus species IgG Ab

6

3

Strongyloides ratti IgG Ab

6

2

Taenia solium IgG Ab

6

2

Trichinella spiralis IgG Ab

6

3

Trypanosoma cruzi IgG Ab

6

1

 

The reference range for the NovaTec S mansoni IgG ELISA was established by testing serum from 50 normal donors; 47/50 (94%) of healthy individuals were negative by this ELISA.

Day(s) Performed

Tuesday, Thursday

Report Available

Same day/1 to 5 days

Specimen Retention Time

14 days

Performing Laboratory

Mayo Clinic Laboratories in Rochester

CPT Code Information

86682

LOINC Code Information

Test ID Test Order Name Order LOINC Value
BILHA Schistosoma Ab, IgG, S 33317-9

 

Result ID Test Result Name Result LOINC Value
BILHA Schistosoma Ab, IgG, S 33317-9

Forms

If not ordering electronically, complete, print, and send 1 of the following forms with the specimen:

-Kidney Transplant Test Request

-Infectious Disease Serology Test Request (T916)