Sign in →

Test Code BCGRV Immunoglobulin Gene Rearrangement, PCR, Varies

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Reporting Name

Immunoglobulin Gene Rearrange, V

Specimen Type

Varies


Shipping Instructions


Body fluid or spinal fluid must arrive within 4 days of collection.



Specimen Required


Submit only 1 of the following specimens:

 

Specimen Type: Body fluid

Container/Tube: Sterile container

Specimen Volume: At least 5 mL

Collection Instructions:

1. If the volume is large, pellet cells prior to sending.

2. Send less volume at ambient temperature or as a frozen cell pellet.

Specimen Stability Information:

Body fluid: Ambient 4 days/Refrigerated/Frozen

Cell pellet: Frozen

 

Specimen Type: Paraffin-embedded bone marrow aspirate clot

Container/Tube: Paraffin block

Specimen Stability Information: Ambient 

 

Specimen Type: Frozen tissue

Container/Tube: Plastic container

Specimen Volume: 100 mg

Collection Instructions: Freeze tissue within 1 hour of collection.

Specimen Stability Information: Frozen

 

Specimen Type: Paraffin-embedded tissue

Container/Tube: Paraffin block

Specimen Stability Information: Ambient

 

Specimen Type: Tissue

Slides: Unstained slides

Specimen Volume: 10 Slides

Specimen Stability Information: Ambient

 

Specimen Type: Spinal fluid

Container/Tube: Sterile vial

Specimen Volume: 5 to 10 mL

Specimen Stability Information: Ambient 4 days/Refrigerated

 

Specimen Type: Extracted DNA

Container/Tube: 1.5- to 2-mL tube

Specimen Volume: Entire specimen

Collection Instructions:

1. Label specimen as extracted DNA and source of specimen

2. Indicate volume and concentration of DNA on label

Specimen Stability Information: Refrigerated/Ambient


Reject Due To

Bone marrow core biopsies
Paraffin shavings		 Reject

Specimen Stability Information

Specimen Type Temperature Time Special Container
Varies Varies

Specimen Minimum Volume

Body and spinal fluid: 1 mL
Tissue: 50 mg
Extracted DNA: 50 microliters (mcL) at 20 ng/mcL

Day(s) Performed

Monday through Friday

Specimen Retention Time

DNA: 3 months

Report Available

7 to 14 days

Reference Values

An interpretive report will be provided.

Useful For

Determining whether a B-cell or plasma cell population is polyclonal or monoclonal in specimens other than blood or bone marrow

 

Identifying neoplastic cells as having B-cell or plasma cell differentiation

 

Monitoring for a persistent neoplasm by detecting an immunoglobulin gene rearrangement profile similar to that from a previous neoplastic specimen

Testing Algorithm

The following algorithms are available:

-Gastric MALT Lymphoma Diagnostic Algorithm      

-Gastric MALT Posttherapy Follow-up Algorithm

CPT Code Information

81261-IGH (Immunoglobulin heavy chain locus) (eg, leukemias and lymphomas B-cell), gene rearrangement analysis to detect abnormal clonal populations; amplified methodology (eg. polymerase chain reaction)

81264-IGK (Immunoglobulin kappa light chain locus) (eg, leukemia and lymphoma, B-cell) gene rearrangement analysis, evaluation to detect abnormal clonal populations

LOINC Code Information

Test ID Test Order Name Order LOINC Value
BCGRV Immunoglobulin Gene Rearrange, V 61113-7

 

Result ID Test Result Name Result LOINC Value
MP017 Specimen: 31208-2
19915 Final Diagnosis: 34574-4
608950 Signing Pathologist 19139-5

Forms

1. Hematopathology Patient Information (T676)

2. If not ordering electronically, complete, print, and send a Hematopathology/Cytogenetics Test Request (T726) with the specimen.