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HelpTest Code APTTP Activated Partial Thromboplastin Time, Plasma
Useful For
Monitoring heparin therapy (unfractionated heparin)
Screening for certain coagulation factor deficiencies
Detection of coagulation inhibitors such as lupus anticoagulant, specific factor inhibitors, and nonspecific inhibitors
Reporting Name
Activated Partial Thrombopl Time, PSpecimen Type
Plasma Na CitOrdering Guidance
The primary method for therapeutic heparin monitoring is the heparin anti-Xa assay. Order HEPTP / Heparin Anti-Xa Assay, Plasma.
Specimen Required
Specimen Type: Platelet-poor plasma
Collection Container/Tube: Light-blue top (3.2% sodium citrate)
Submission Container/Tube: Plastic vial
Specimen Volume: 1 mL
Collection Instructions:
1. Centrifuge, remove plasma and centrifuge plasma again.
2. Aliquot plasma into plastic vial leaving 0.25 mL in the bottom of centrifuged vial.
Additional Information: Double-centrifuged specimen is critical for accurate results as platelet contamination may cause spurious results.
Specimen Minimum Volume
0.5 mL
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Plasma Na Cit | Frozen (preferred) | 30 days | |
| Ambient | 4 hours |
Reject Due To
| Gross hemolysis | Reject |
| Gross lipemia | OK |
| Gross icterus | OK |
Reference Values
25-37 seconds
Supportive Data
The activated partial thromboplastin time (APTT) reference interval of 25 to 37 seconds was determined by verifying the IL package insert.
Day(s) Performed
Monday through Sunday
Report Available
Same day/1 daySpecimen Retention Time
24 hoursPerforming Laboratory
Mayo Clinic Laboratories in Rochester
CPT Code Information
85730
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| APTTP | Activated Partial Thrombopl Time, P | 14979-9 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| APTTP | Activated Partial Thrombopl Time, P | 14979-9 |