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HelpTest Code AFPA Alpha-Fetoprotein, Amniotic Fluid
Performing Laboratory
Mayo Clinic Laboratories in Rochester
Reporting Name
Alpha Fetoprotein, AFSpecimen Type
Amniotic FldNecessary Information
The following information is required:
1. Estimated due date by ultrasound
2. Collection date
3. Gestational age must be between 13 and 24 weeks; 16 to 18 weeks preferred.
If not ordering electronically, provide information on Second Trimester Maternal Screening Alpha-Fetoprotein / Quad Screen Patient Information (T595) and send with specimen.
Specimen Required
Container/Tube: Amniotic fluid container
Specimen Volume: 0.75 mL
Collection Instructions: Do not centrifuge.
Reject Due To
All specimens will be evaluated at Mayo Clinic Laboratories for test suitability.Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Amniotic Fld | Refrigerated (preferred) | 7 days | |
| Ambient | 7 days |
Specimen Minimum Volume
0.5 mL
Special Instructions
Day(s) Performed
Monday through Friday
Specimen Retention Time
2 weeksReport Available
2 to 19 daysReference Values
< 2.0 multiples of median (MoM)
Reflex Tests
| Test ID | Reporting Name | Available Separately | Always Performed |
|---|---|---|---|
| ACHE_ | Acetylcholinesterase, AF | Yes | No |
Useful For
Screening for open neural tube defects or other fetal abnormalities
Follow-up testing for patients with elevated serum alpha-fetoprotein results or in conjunction with cytogenetic testing
Testing Algorithm
If alpha-fetoprotein is positive, then acetylcholinesterase will be performed at an additional charge.
CPT Code Information
82106
82013 (if appropriate)
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| AFPA | Alpha Fetoprotein, AF | 58735-2 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| 6739 | Collection Date | 58734-5 |
| DAT15 | EDD by US Scan | 11781-2 |
| 6740 | Last Menstrual Period (LMP) | 8665-2 |
| 24233 | EDD by LMP | 11779-6 |
| 24239 | GA at Collection by Scan | 11888-5 |
| 24240 | GA at Collection by Dates | 11885-1 |
| 24234 | GA Used | 21299-3 |
| 9950 | Alpha Fetoprotein, AF | 1832-5 |
| 24241 | Results | 29595-6 |
| 24235 | Interpretation | 59462-2 |
| 24236 | Additional Comments | 48767-8 |
| 24237 | Follow up | 80615-8 |
| 24238 | General Test Info | 48767-8 |
Forms
Second Trimester Maternal Screening Alpha-Fetoprotein / Quad Screen Patient Information (T595) is required.