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Test Code VANPRE/LAB39 Vancomycin, Pre/Trough

Performing Laboratory

Asante Rogue Regional Medical Center / Asante Three Rivers Medical Center / Ashland Community Hospital

Specimen Requirements


Yellow (Gold) top tube (SST)  

Lithium Heparin Green top tube

Outpatient clients MUST draw SST



Plain Red top tube   No SST or PST


For TROUGH level, collect 15 minutes before the next dose. Pre and Post labeling of samples is critical.
Please provide last dose information.

Specimen Transport Temperature and Stability

Centrifuge and refrigerate within 2 hours of collection

Primary tube: Spun SST stable 48 hours at  2° to 8° C

Serum stable 48 hours if aliquoted and refrigerated at 2° to 8° C

Specimen Minimum Volume

0.5 mL

Reasons for Rejection




Quantity not sufficient (QNS)

Lack of Two Patient Identifiers:

         1-Patient's First & Last name 

         2-Patient's Date of Birth

Day(s) Test Set Up

Routine – same day

ASAP – 2 hours after receipt of specimen in lab

STAT – 1 hour after receipt of specimen in lab

Additional Information

Used to monitor therapeutic levels.  Vancomycin has regained clinical popularity for the treatment of
methicillin-resistant Staphylococcus aureus and antibiotic-associated diarrhea due to Clostridium difficile. 
The drug is otonephrotoxic and the toxicity may be synergistic with that of aminoglycosides. 

Renal and auditory function should be monitored.


Turbidimetric Immunoassay 

Performing Department


Test Classification and CPT Coding

80202  -  Vancomycin, Therapeutic Drug Assay 

Billing Code