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Test Code VANPA Vancomycin, Peak, Serum

Useful For

Monitoring peak levels in selected patients receiving vancomycin therapy

Reporting Name

Vancomycin, Peak, S

Specimen Type

Serum Red


Ordering Guidance


In addition to this peak assay, both trough level and random testing are available.

1. Serum for a trough level should be drawn no more than 30 minutes prior to next dose; order VANTA / Vancomycin, Trough, Serum.

2. Serum for random testing should be ordered as VANRA / Vancomycin, Random, Serum.



Specimen Required


Collection Container/Tube: Red top

Submission Container/Tube: Plastic vial

Specimen Volume: 0.5 mL

Collection Instructions:

1. Serum for a peak level should be drawn 1 hour after completion of dose.

2. Centrifuge and aliquot serum into a plastic vial within 2 hours of collection.


Specimen Minimum Volume

0.25 mL

Specimen Stability Information

Specimen Type Temperature Time
Serum Red Refrigerated (preferred) 14 days
  Frozen  365 days
  Ambient  48 hours

Reject Due To

Gross hemolysis Reject

Reference Values

Therapeutic: 20.0-45.0 mcg/mL

Method Description

The assay is based on the kinetic interaction of microparticles in solution (KIMS). Vancomycin antibody is covalently coupled to microparticles and the derivative is linked to a macromolecule. The kinetic interaction of microparticles in solutions is induced by binding of drug-conjugate to the antibody on the microparticles and is inhibited by the presence of vancomycin in the sample. A competitive reaction takes place between the drug conjugate and vancomycin in the sample. A competitive reaction takes place between the drug conjugate and vancomycin in the serum sample for binding to the vancomycin antibody on the microparticles. The resulting kinetic interaction of microparticles is indirectly proportional to the amount of drug present in the sample.(Package insert: Roche Vancomycin reagent, Roche Diagnostic Corp, Indianapolis, IN.  2016-09 Ver. 1)

Day(s) Performed

Monday through Sunday

Report Available

Same day/1 to 2 days

Specimen Retention Time

1 week

Performing Laboratory

Mayo Clinic Laboratories in Rochester

CPT Code Information

80202

LOINC Code Information

Test ID Test Order Name Order LOINC Value
VANPA Vancomycin, Peak, S 4090-7

 

Result ID Test Result Name Result LOINC Value
VANPA Vancomycin, Peak, S 4090-7

Forms

If not ordering electronically, complete, print, and send a Therapeutics Test Request (T831) with the specimen.