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Test Code TIBC Total Iron Binding Capacity, Serum


Specimen Required


Only orderable as part of profile. For more information see SFEC / Iron and Total Iron Binding Capacity, Serum

 

Patient Preparation:

1. Fasting: 8 hours, preferred but not required

2. For 24 hours before collection, patient should not take iron-containing supplements.

 

Supplies: Sarstedt Aliquot Tube 5 mL (T914)

Container/Tube:

Preferred: Serum gel

Acceptable: Red top

Submission Container/Tube: Plastic vial

Specimen Volume: 1 mL

Collection Instructions:

1. Draw blood before noon (preferred).

2. Within 2 hours of collection, serum gel tubes should be centrifuged.

3. Within 2 hours of collection, red-top tubes should be centrifuged, and the serum aliquoted into a plastic vial.


Useful For

Screening for chronic iron overload diseases, particularly hereditary hemochromatosis

Reporting Name

Total Iron Binding Capacity

Specimen Type

Serum

Specimen Minimum Volume

0.5 mL

Specimen Stability Information

Specimen Type Temperature Time
Serum Refrigerated (preferred) 21 days
  Frozen  365 days

Reject Due To

Gross hemolysis Reject
Gross lipemia OK
Gross icterus OK

Reference Values

Only orderable as part of profile. For more information see SFEC / Iron and Total Iron-Binding Capacity, Serum.

 

250-400 mcg/dL

Method Description

Transferrin:

Anti-transferrin antibodies react with the antigen in the sample to form an antigen/antibody complex. Following agglutination, this is measured turbidimetrically. Addition of polyethylene glycol allows the reaction to progress rapidly to the end point and increases sensitivity. The result is used to calculate the total iron-binding capacity and is not included on the report.(Package insert: TRSF2. Roche Diagnostics; v10.0, 04/2022)

 

Total Iron-Binding Capacity:

This test calculates the total iron-binding capacity (TIBC) using results obtained from transferrin analysis. The following calculation is performed in the laboratory information system.

TIBC = Transferrin x 1.18

Day(s) Performed

Monday through Sunday

Report Available

Same day/1 to 2 days

Specimen Retention Time

7 days

Performing Laboratory

Mayo Clinic Laboratories in Rochester

CPT Code Information

83550

LOINC Code Information

Test ID Test Order Name Order LOINC Value
TIBC Total Iron Binding Capacity 2500-7

 

Result ID Test Result Name Result LOINC Value
TIBC Total Iron Binding Capacity 2500-7