Test Code SALCA Salicylate, Serum
Useful For
Quantitative determination of toxic levels of salicylate
This test is not useful for assessing low-dose aspirin therapy.
Reporting Name
Salicylate, SSpecimen Type
SerumSpecimen Required
Collection Container/Tube:
Preferred: Serum gel
Acceptable: Red top
Submission Container/Tube: Plastic vial
Specimen Volume: 0.5 mL
Collection Instructions:
1. Serum gel tubes should be centrifuged within 2 hours of collection.
2. Red-top tubes should be centrifuged, and the serum aliquoted into a plastic vial within 2 hours of collection.
Specimen Minimum Volume
0.25 mL
Specimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Serum | Refrigerated (preferred) | 7 days |
| Frozen | 28 days | |
| Ambient | 72 hours |
Reject Due To
| Gross hemolysis | Reject |
Reference Values
Therapeutic: <30.0 mg/dL
Critical value: ≥50.0 mg/dL
Method Description
This determination depends upon the conversion of salicylate in the presence of the reduced form of nicotinamide adenine dinucleotide (NADH) by salicylate hydroxylase to catechol and nicotinamide adenine dinucleotide (NAD). The concomitant conversion of NADH to NAD is measured by the decrease in absorbance at 340 nm. The decrease is proportional to the concentration of salicylate present in the sample.(Package insert: Roche SALI reagent. Roche Diagnostics Corp; 11/2023)
Day(s) Performed
Monday through Sunday
Report Available
Same day/1 daySpecimen Retention Time
1 weekPerforming Laboratory
Mayo Clinic Laboratories in Rochester
CPT Code Information
80179
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| SALCA | Salicylate, S | 4024-6 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| SALCA | Salicylate, S | 4024-6 |