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Test Code SALCA Salicylate, Serum

Useful For

Quantitative determination of toxic levels of salicylate

 

This test is not useful for assessing low-dose aspirin therapy.

Reporting Name

Salicylate, S

Specimen Type

Serum


Specimen Required


Collection Container/Tube:

Preferred: Serum gel

Acceptable: Red top

Submission Container/Tube: Plastic vial

Specimen Volume: 0.5 mL

Collection Instructions:

1. Serum gel tubes should be centrifuged within 2 hours of collection.

2. Red-top tubes should be centrifuged, and the serum aliquoted into a plastic vial within 2 hours of collection.


Specimen Minimum Volume

0.25 mL

Specimen Stability Information

Specimen Type Temperature Time
Serum Refrigerated (preferred) 7 days
  Frozen  28 days
  Ambient  72 hours

Reject Due To

Gross hemolysis Reject

Reference Values

Therapeutic: <30.0 mg/dL

Critical value: ≥50.0 mg/dL

Method Description

This determination depends upon the conversion of salicylate in the presence of the reduced form of nicotinamide adenine dinucleotide (NADH) by salicylate hydroxylase to catechol and nicotinamide adenine dinucleotide (NAD). The concomitant conversion of NADH to NAD is measured by the decrease in absorbance at 340 nm. The decrease is proportional to the concentration of salicylate present in the sample.(Package insert: Roche SALI reagent. Roche Diagnostics Corp; 11/2023)

Day(s) Performed

Monday through Sunday

Report Available

Same day/1 day

Specimen Retention Time

1 week

Performing Laboratory

Mayo Clinic Laboratories in Rochester

CPT Code Information

80179

LOINC Code Information

Test ID Test Order Name Order LOINC Value
SALCA Salicylate, S 4024-6

 

Result ID Test Result Name Result LOINC Value
SALCA Salicylate, S 4024-6