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Test Code RAPAN Rheumatoid Arthritis Panel, Serum


Ordering Guidance


This test is the optimal first-line antibody panel for evaluating patients at-risk for rheumatoid arthritis.

The following testing may also be useful:

ENAE / Antibody to Extractable Nuclear Antigen Evaluation, Serum

ADNA1 / Double-Stranded DNA (dsDNA) Antibodies , IgG, Serum

NAIFA / Antinuclear Antibodies, HEp-2 Substrate, IgG, Serum

CTDC / Connective Tissue Diseases Cascade, Serum



Specimen Required


Supplies: Sarstedt Aliquot Tube, 5 mL (T914)

Collection Container/Tube:

Preferred: Serum gel

Acceptable: Red top

Submission Container/Tube: Plastic vial

Specimen Volume: 2 mL

Collection Instructions: Centrifuge and aliquot serum into a plastic vial.


Useful For

Evaluating patients suspected of having rheumatoid arthritis (RA)

 

Differentiating RA from other inflammatory arthritis or connective tissue diseases

 

Diagnosis and stratification of rheumatoid arthritis

Profile Information

Test ID Reporting Name Available Separately Always Performed
CCP Cyclic Citrullinated Peptide Ab, S Yes Yes
RHUT Rheumatoid Factor, S Yes Yes

Special Instructions

Reporting Name

Rheumatoid Arthritis Panel, S

Specimen Type

Serum

Specimen Minimum Volume

1.2 mL

Specimen Stability Information

Specimen Type Temperature Time
Serum Refrigerated (preferred) 14 days
  Frozen  14 days

Reject Due To

Gross hemolysis Reject
Gross lipemia Reject
Gross icterus OK
Heat-treated specimen Reject

Reference Values

Cyclic Citrullinated Peptide Antibodies, IgG

<20.0 U (negative)

20.0-39.9 U (weak positive)

40.0-59.9 U (positive)

≥60.0 U (strong positive)

Reference values apply to all ages.

 

Rheumatoid Factor

<15 IU/mL

Day(s) Performed

Monday through Saturday

Report Available

2 to 3 days

Specimen Retention Time

14 days

Performing Laboratory

Mayo Clinic Laboratories in Rochester

CPT Code Information

86200

86431

LOINC Code Information

Test ID Test Order Name Order LOINC Value
RAPAN Rheumatoid Arthritis Panel, S 46437-0

 

Result ID Test Result Name Result LOINC Value
CCP Cyclic Citrullinated Peptide Ab, S 33935-8
RHUT Rheumatoid Factor, S 11572-5