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Test Code PK1 Pyruvate Kinase Enzyme Activity, Blood


Specimen Required


Collection Container/Tube:

Preferred: Yellow top (ACD solution B)

Acceptable: Lavender top (EDTA)

Specimen Volume: 6 mL

Collection Instructions:  Send whole blood specimen in original tube. Do not aliquot.


Useful For

Evaluation of nonspherocytic hemolytic anemia

 

Evaluation of neonatal anemia or jaundice

 

Evaluation of unexplained noninfectious hepatic failure

 

Evaluation of unexplained iron overload

 

Evaluation of unusually severe hemoglobin S trait

 

Evaluation of unusually severe glucose 6-phosphate dehydrogenase deficiency

 

Investigating families with pyruvate kinase deficiency to determine inheritance pattern and for genetic counseling

Reporting Name

PK Enzyme Activity, B

Specimen Type

Whole Blood ACD-B

Specimen Minimum Volume

1 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Whole Blood ACD-B Refrigerated 20 days

Reject Due To

Gross hemolysis Reject

Reference Values

≥12 months of age: 5.5-12.4 U/g Hb

Reference values have not been established for patients who are younger than 12 months.

Specimen Retention Time

7 days

Performing Laboratory

Mayo Clinic Laboratories in Rochester

CPT Code Information

84220

LOINC Code Information

Test ID Test Order Name Order LOINC Value
PK1 PK Enzyme Activity, B 32552-2

 

Result ID Test Result Name Result LOINC Value
PKCL PK Enzyme Activity, B 32552-2

Day(s) Performed

Monday through Friday

Report Available

1 to 4 days

Forms

If not ordering electronically, complete, print, and send a Benign Hematology Test Request (T755) with the specimen.