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HelpTest Code PFCEA Carcinoembryonic Antigen (CEA), Pleural Fluid
Performing Laboratory
Mayo Clinic Laboratories in Rochester
Reporting Name
CEA, Pleural FluidSpecimen Type
Pleural FluidSpecimen Required
Sources: Pleural fluid, thoracentesis fluid
Container/Tube: Plain, plastic, screw-top tube
Specimen Volume: 2 mL
Reject Due To
| Gross hemolysis | Reject |
Specimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Pleural Fluid | Frozen (preferred) | 90 days |
| Refrigerated | 14 days | |
| Ambient | 7 days |
Specimen Minimum Volume
0.5 mL
Day(s) Performed
Monday through Saturday
Specimen Retention Time
14 daysReport Available
1 to 3 daysReference Values
An interpretive report will be provided.
Useful For
An adjuvant to cytology and imaging studies to differentiate between nonmalignant and malignant causes of pleural effusions
CPT Code Information
82378
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| PFCEA | CEA, Pleural Fluid | 19169-2 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| PCEA | CEA, Pleural Fluid | 19169-2 |
| SITE9 | Site | 39111-0 |
Method Description
The instrument used is Beckman Coulter UniCel DXI 800. The Access CEA assay is a 2-site immunoenzymatic sandwich assay using mouse monoclonal carcinoembryonic antigen (CEA) antibodies that react with different epitopes of CEA. A sample is added to a reaction vessel, along with the first CEA monoclonal antibody-alkaline phosphatase conjugate and the second CEA monoclonal antibody bound to paramagnetic particles. The incubation is followed by magnetic separation and washing. A chemiluminescent substrate is added to the vessel, and the light generated by the reaction is measured with a luminometer. The light production is proportional to the concentration of CEA in the sample. The amount of analyte in the sample is determined by means of a stored, multipoint calibrator curve.(Package insert: Access CEA Assay, Beckman Coulter, Inc; 2020)
Forms
If not ordering electronically, complete, print, and send an Oncology Test Request (T729) with the specimen.