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HelpTest Code PETNU Phosphoethanolamine, Quantitative, Random, Urine
Necessary Information
1. Patient's age is required.
2. Include family history, clinical condition (asymptomatic or acute episode), diet, and drug therapy information.
Specimen Required
Supplies: Urine Tubes, 10 mL (T068)
Container/Tube: Clean plastic urine tube
Specimen Volume: 2 mL
Collection Instructions:
1. Collect a random urine specimen.
2. No preservative.
Useful For
To aid in the diagnosis of hypophosphatasia, especially in the setting of low alkaline phosphatase, bone fractures, and early tooth loss
Monitoring of affected individuals on therapy
Reporting Name
Phosphoethanolamine, QN, Random, USpecimen Type
UrineSpecimen Minimum Volume
1 mL
Specimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Urine | Frozen (preferred) | 70 days |
| Refrigerated | 14 days |
Reject Due To
All specimens will be evaluated at Mayo Clinic Laboratories for test suitability.Reference Values
≤12 months: 15-341 nmol/mg creatinine
13-35 months: 33-342 nmol/mg creatinine
3-6 years: 19-164 nmol/mg creatinine
7-8 years: 12-118 nmol/mg creatinine
9-17 years: <88 nmol/mg creatinine
≥18 years: <48 nmol/mg creatinine
An interpretative report will be provided.
Method Description
Quantitative analysis of phosphoethanolamine (PEA) is performed by liquid chromatography tandem mass spectrometry (LC-MS/MS) by labeling PEA present in urine with aTRAQ Reagent 121. Samples are combined with aTRAQ Reagent 113-labeled Standard Mix and partially dried to remove readily volatile solvents. Phosphoethanolamine is separated and detected by LC-MS/MS (Sciex 4500). The concentration of PEA is established by comparison of the ion intensity (121-labeled PEA) to that of the internal standard (113-labeled PEA).(Unpublished Mayo method)
Day(s) Performed
Tuesday
Report Available
3 to 9 daysSpecimen Retention Time
2 weeksPerforming Laboratory
Mayo Clinic Laboratories in Rochester
CPT Code Information
82131
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| PETNU | Phosphoethanolamine, QN, Random, U | In Process |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| 623432 | Interpretation | 59462-2 |
| 623430 | Phosphoethanolamine | 28604-7 |
| 623431 | Reviewed By | 18771-6 |