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Test Code OXYDS Oxycodone and Metabolites, Serum


Ordering Guidance


This test should only be ordered by healthcare professionals to monitor patients who have been prescribed oxycodone and/or oxymorphone.



Specimen Required


Supplies: Sarstedt Aliquot Tube, 5 mL (T914)

Collection Container/Tube: Red top (Serum gel/SST are not acceptable)

Submission Container/Tube: Plastic vial

Specimen Volume: 1 mL serum

Collection Instructions: Centrifuge and aliquot serum into a plastic vial.


Useful For

Monitoring therapeutic efficacy/compliance in serum specimens of patients who are prescribed oxycodone and/or oxymorphone

 

Detection and quantification of oxycodone, oxymorphone, noroxycodone, and noroxymorphone in serum

Reporting Name

Oxycodone and metabolites, S

Specimen Type

Serum Red

Specimen Minimum Volume

Serum: 0.5 mL

Specimen Stability Information

Specimen Type Temperature Time
Serum Red Refrigerated (preferred) 14 days
  Frozen  28 days
  Ambient  24 hours

Reject Due To

Gross hemolysis Reject
Gross lipemia OK
Gross icterus OK

Reference Values

Therapeutic range/Metabolite information (as applicable):

Oxycodone: 10-100 ng/mL

Noroxycodone: Metabolite of oxycodone

Oxymorphone: Metabolite of oxycodone; 1.0-8.0 ng/mL when used as sole therapy

Noroxymorphone: Metabolite of oxymorphone

 

Cutoff concentrations:

Oxycodone: 1.0 ng/mL

Noroxycodone: 1.0 ng/mL

Oxymorphone: 1.0 ng/mL

Noroxymorphone: 1.0 ng/mL

Day(s) Performed

Wednesday

Report Available

2 to 9 days

Specimen Retention Time

14 days

Performing Laboratory

Mayo Clinic Laboratories in Rochester

CPT Code Information

G0480

80365 (if appropriate for select payers)

Clinical Toxicology CPT Code Client Guidance

LOINC Code Information

Test ID Test Order Name Order LOINC Value
OXYDS Oxycodone and metabolites, S In Process

 

Result ID Test Result Name Result LOINC Value
623456 Oxycodone - Free 12789-4
623457 Noroxycodone - Free In Process
623458 Oxymorphone - Free 46974-2
623459 Noroxymorphone - Free In Process