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HelpTest Code MONOF Monocyte Repartition by CD14/CD16, Blood
Ordering Guidance
If cytogenetic tests are requested in addition to this test, an additional specimen tube should be submitted. It is important that the specimen be obtained, processed, and transported according to instructions for the other required test
Shipping Instructions
Specimens must be refrigerated and received within 3 days of collection.
Specimen Required
Container/Tube:
Preferred: Yellow top (ACD solution A or B)
Acceptable: Lavender top (EDTA)
Specimen Volume: 3 mL
Collection Instructions: Send whole blood specimen in original tube. Do not aliquot.
Useful For
Aiding in the diagnosis and monitoring of chronic myelomonocytic leukemia
Reporting Name
Monocyte Repartition by CD14/CD16,BSpecimen Type
Whole bloodSpecimen Minimum Volume
1 mL
Specimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Whole blood | Refrigerated | 72 hours |
Reject Due To
| Gross hemolysis | Reject |
Reference Values
% Monocytes of WBC: 1.0-6.6%
MO1 (classical monocytes): <94.0%
Supportive Data
Clinical Sensitivity and Sensitivity:
Thirty-two patients with untreated chronic myelomonocytic leukemia (CMML) were tested. Twenty-five of these patients had a percent classical monocyte (%MO1) result of greater than or equal to 94% (abnormal result), which correlated to a sensitivity of 78%.
One hundred one patients with non-CMML hematologic malignancies were also tested. Ninety of these patients had a %MO1 result of less than 94% (normal result), which correlated to a specificity of 89%.
In addition, 30 healthy donors also had a %MO1 result of less than 94% (normal result).
Specimen Retention Time
14 daysPerforming Laboratory
Mayo Clinic Laboratories in Rochester
CPT Code Information
88184-Flow cytometry; first cell surface, cytoplasmic or nuclear marker
88185 x 7-Flow cytometry; additional cell surface, cytoplasmic or nuclear marker (each)
88187-Flow Cytometry Interpretation, 2 to 8 markers
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| MONOF | Monocyte Repartition by CD14/CD16,B | 101146-9 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| 610019 | % Monocytes of WBC | 101147-7 |
| 610020 | MO1 (Classical Monocytes) | 101148-5 |
| 610023 | Final Diagnosis | In Process |
Day(s) Performed
Monday through Saturday