Test Code MB2GP Beta-2 Glycoprotein 1 Antibodies, IgM, Serum
Performing Laboratory
Mayo Clinic Laboratories in RochesterReporting Name
Beta 2 GP1 Ab IgM, SSpecimen Type
SerumAdditional Testing Requirements
Diagnostic criteria for antiphospholipid syndrome include the presence of at least one of the following: lupus anticoagulant, anticardiolipin, and anti-beta-2 glycoprotein 1 IgG or IgM antibodies. Consider ordering CLPMG / Phospholipid (Cardiolipin) Antibodies, IgG and IgM, Serum; GB2GP / Beta-2 Glycoprotein 1 Antibodies, IgG, Serum; and ALUPP / Lupus Anticoagulant Profile, Plasma concurrently with this test.
Specimen Required
Collection Container/Tube:
Preferred: Serum gel
Acceptable: Red top
Submission Container/Tube: Plastic vial
Specimen Volume: 0.5 mL
Collection Instructions: Centrifuge and aliquot serum into a plastic vial.
Reject Due To
Gross hemolysis | Reject |
Gross lipemia | Reject |
Gross icterus | OK |
Heat-treated specimens | Reject |
Specimen Stability Information
Specimen Type | Temperature | Time | Special Container |
---|---|---|---|
Serum | Refrigerated (preferred) | 21 days | |
Frozen | 21 days |
Specimen Minimum Volume
0.4 mL
Day(s) Performed
Monday through Saturday
Specimen Retention Time
14 daysReport Available
2 to 6 daysReference Values
<15.0 SMU (negative)
15.0-39.9 SMU (weakly positive)
40.0-79.9 SMU (positive)
≥80.0 SMU (strongly positive)
Results are reported in standard IgM anti-beta 2 glycoprotein 1 units (SMU).
Reference values apply to all ages.
Useful For
Evaluating patients with suspected antiphospholipid syndrome by identification of beta-2 glycoprotein 1 IgM antibodies
First-line test when antiphospholipid syndrome is strongly suspected in conjunction with cardiolipin antibodies (IgG and IgM) and lupus anticoagulant testing
Estimating the risk of thrombosis and/or pregnancy-related morbidity in patients with systemic lupus erythematosus
CPT Code Information
86146
LOINC Code Information
Test ID | Test Order Name | Order LOINC Value |
---|---|---|
MB2GP | Beta 2 GP1 Ab IgM, S | 44449-7 |
Result ID | Test Result Name | Result LOINC Value |
---|---|---|
MB2GP | Beta 2 GP1 Ab IgM, S | 44449-7 |