Test Code LAB887 Hepatitis C Virus (HCV) RNA Detection and Quantification by Real-Time Reverse Transcription-PCR, Serum
Ordering Guidance
For detection and quantification of hepatitis C viral RNA in serum before, during, and after antiviral therapy for chronic hepatitis C.
Shipping Instructions
1. Freeze serum immediately, and ship specimen frozen on dry ice only.
2. If shipment will be delayed for more than 24 hours, freeze serum at -20 to -80° C (up to 84 days) until shipment on dry ice.
Specimen Required
Supplies: Sarstedt 5 mL Aliquot Tube (T914)
Collection Container/Tube: Serum gel
Submission Container/Tube: Plastic vial
Specimen Volume: 1.5 mL
Collection Instructions: Centrifuge and aliquot serum into plastic vial within 2 hours of collection.
Useful For
Detection of acute hepatitis C virus (HCV) infection before the appearance of HCV antibodies in serum (ie, <2 months from exposure)
Detection and confirmation of chronic HCV infection
Quantification of HCV RNA in serum of patients with chronic HCV infection (HCV antibody-positive)
Monitoring disease progression in chronic HCV infection and response to antiviral therapy
Determining cure and detection of relapse after completion of antiviral therapy
Testing Algorithm
For more information see:
-Chronic Hepatitis C Treatment and Monitoring Algorithm: Direct Antiviral Antigen (DAA) Combination
Special Instructions
Reporting Name
HCV RNA Detect/Quant, SSpecimen Type
Serum SSTSpecimen Minimum Volume
0.8 mL
Specimen Stability Information
Specimen Type | Temperature | Time | Special Container |
---|---|---|---|
Serum SST | Frozen (preferred) | 84 days | |
Refrigerated | 6 days |
Reject Due To
Gross hemolysis | OK |
Gross lipemia | OK |
Gross icterus | OK |
Reference Values
Undetected
Day(s) Performed
Monday through Saturday
Report Available
1 to 3 daysSpecimen Retention Time
2 monthsPerforming Laboratory
Mayo Clinic Laboratories in RochesterCPT Code Information
87522
LOINC Code Information
Test ID | Test Order Name | Order LOINC Value |
---|---|---|
HCVQN | HCV RNA Detect/Quant, S | 11011-4 |
Result ID | Test Result Name | Result LOINC Value |
---|---|---|
97291 | HCV RNA Detect/Quant, S | 11011-4 |
Forms
If not ordering electronically, complete, print, and send 1 of the following forms with the specimen:
-Gastroenterology and Hepatology Test Request (T728)
-Microbiology Test Request (T244)
-General Test Request (T239)