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HelpTest Code LAB857 Intrinsic Factor Blocking Antibody, Serum
Performing Laboratory
Mayo Clinic Laboratories in Rochester
Reporting Name
Intrinsic Factor Blocking Ab, SSpecimen Type
SerumOrdering Guidance
For a comprehensive workup of patients with suspected pernicious anemia, order ACASM / Pernicious Anemia Cascade, Serum, which initiates testing with measurement of vitamin B12. Depending of the vitamin B12 concentration, testing for intrinsic factor blocking antibody, gastrin, and methylmalonic acid may be added.
Specimen Required
Patient Preparation:
1. Patient should be fasting for 8 hours.
2. This test should not be performed on patients who have received a vitamin B12 injection or radiolabeled vitamin B12 injection within the previous 2 weeks.
Collection Container/Tube:
Preferred: Serum gel
Acceptable: Red top
Submission Container/Tube: Plastic vial
Specimen Volume: 1 mL
Collection Instructions: Centrifuge and aliquot serum into a plastic vial.
Reject Due To
| Gross hemolysis | Reject |
| Gross lipemia | OK |
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Serum | Refrigerated (preferred) | 14 days | |
| Frozen | 14 days |
Specimen Minimum Volume
0.5 mL
Special Instructions
Day(s) Performed
Monday through Friday
Specimen Retention Time
2 weeksReport Available
1 day to 3 daysReference Values
Negative
Useful For
Confirming the diagnosis of pernicious anemia
Testing Algorithm
For more information, see Vitamin B12 Deficiency Evaluation.
CPT Code Information
86340
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| IFBA | Intrinsic Factor Blocking Ab, S | 31444-3 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| IFBLA | Intrinsic Factor Blocking Ab, S | 31444-3 |
| CMT31 | Comment | 48767-8 |