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HelpTest Code LAB759 Antithrombin Activity, Plasma
Performing Laboratory
Mayo Clinic Laboratories in Rochester
Reporting Name
Antithrombin Activity, PSpecimen Type
Plasma Na CitOrdering Guidance
Coagulation testing is highly complex, often requiring the performance of multiple assays and correlation with clinical information. For that reason, consider ordering AATHR / Thrombophilia Profile, Plasma and Whole Blood.
Specimen Required
Specimen Type: Platelet-poor plasma
Collection Container/Tube: Light-blue top (3.2% sodium citrate)
Submission Container/Tube: Plastic vial
Specimen Volume: 1 mL
Collection Instructions:
1. For complete instructions, see Coagulation Guidelines for Specimen Handling and Processing.
2. Centrifuge, transfer all plasma into a plastic vial, and centrifuge plasma again.
3. Aliquot plasma into a plastic vial leaving 0.25 mL in the bottom of centrifuged vial.
4. Freeze plasma immediately (no longer than 4 hours after collection) at -20° C or, ideally at -40° C or below.
Additional Information:
1. A double-centrifuged specimen is critical for accurate results as platelet contamination may cause spurious results.
2. Each coagulation assay requested should have its own vial.
3. Heparin treatment may lower plasma antithrombin.
Reject Due To
| Gross hemolysis | Reject |
| Gross lipemia | Reject |
| Gross icterus | Reject |
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Plasma Na Cit | Frozen | 14 days |
Specimen Minimum Volume
0.5 mL
Special Instructions
Day(s) Performed
Monday through Saturday
Specimen Retention Time
7 daysReport Available
1 to 3 daysReference Values
Normal values: 80-130%
Normal, full-term newborn infants have lower levels (≥35-40%) that reach normal values by age 90 days. Premature infants (30-36 weeks gestation) have lower levels that reach normal values by age 180 days.
Useful For
Diagnosis of antithrombin deficiency, acquired or congenital
Monitoring treatment of antithrombin deficiency disorders, including infusion of antithrombin therapeutic concentrate
CPT Code Information
85300
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| ATTF | Antithrombin Activity, P | 27811-9 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| ATTF | Antithrombin Activity, P | 27811-9 |
Forms
If not ordering electronically, complete, print, and send a Coagulation Test Request (T753) with the specimen.