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Test Code LAB725 Gliadin (Deamidated) Antibodies Evaluation, IgG and IgA, Serum

Important Note

Mayo's test code: DGLDN

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Reporting Name

Gliadin (Deamidated) Ab, Eval, S

Specimen Type

Serum


Ordering Guidance


Cascade testing is recommended for celiac disease. Cascade testing ensures that testing proceeds in an algorithmic fashion. The following cascades are available; select the appropriate one for your specific patient situation.

-CDCOM / Celiac Disease Comprehensive Cascade, Serum and Whole Blood: complete testing including HLA DQ

-CDSP / Celiac Disease Serology Cascade, Serum: complete serology testing excluding HLA DQ

-CDGF / Celiac Disease Gluten-Free Cascade, Serum and Whole Blood: for patients already adhering to a gluten-free diet

To order individual tests, see Celiac Disease Diagnostic Testing Algorithm.



Specimen Required


Collection Container/Tube:

Preferred: Serum gel

Acceptable: Red top

Submission Container/Tube: Plastic vial

Specimen Volume: 0.5 mL

Collection Instructions: Centrifuge and aliquot serum into a plastic vial.


Reject Due To

Gross hemolysis Reject
Gross lipemia Reject
Gross icterus OK

Specimen Stability Information

Specimen Type Temperature Time Special Container
Serum Refrigerated (preferred) 21 days
  Frozen  21 days

Specimen Minimum Volume

0.4 mL

Day(s) Performed

Monday, Wednesday, Friday

Specimen Retention Time

14 days

Report Available

2 to 4 days

Reference Values

Negative: <20.0 U

Weak positive: 20.0-30.0 U

Positive: >30.0 U

Reference values apply to all ages.

Useful For

Assessment of deaminated gliadin IgA and IgG antibodies for evaluating patients suspected of having celiac disease, including patients with compatible clinical symptoms, patients with atypical symptoms, and individuals at increased risk (family history, previous diagnosis with associated disorder, positivity for HLA DQ2 and/or DQ8)

 

Monitoring response to a gluten-free diet in patients with celiac disease.

CPT Code Information

86258 x 2

LOINC Code Information

Test ID Test Order Name Order LOINC Value
DGLDN Gliadin (Deamidated) Ab, Eval, S 57776-7

 

Result ID Test Result Name Result LOINC Value
DAGL Gliadin(Deamidated) Ab, IgA, S 47393-4
DGGL Gliadin(Deamidated) Ab, IgG, S 47394-2

Profile Information

Test ID Reporting Name Available Separately Always Performed
DAGL Gliadin(Deamidated) Ab, IgA, S Yes Yes
DGGL Gliadin(Deamidated) Ab, IgG, S Yes Yes

Forms

If not ordering electronically, complete, print, and send a Gastroenterology and Hepatology Test Request (T728) with the specimen.