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Test Code LAB61 Cortisol

Useful For

Used to establish a diagnosis of adrenocortical insufficiency, Addison’s disease, adrenocortical hypersecretion, Cushing’s disease; malfunction of any of the organs in the hypothalamus, pituitary, adrenal cortex axis will result in alteration of the cortisol levels.  Cortisol is physiologically increased in patients with hypoglycemia, stress, and in pregnancy.

Cortisol Stimulation Test:

(1) Baseline Cortisol
(2) Inject Cortrosyn or equivalent
(3) 30 minute post-injection Cortisol
(4) 60 minute post-injection Cortisol

Cortisol levels usually peak about 45 to 60 minutes after injection of Cortrosyn.  The normal response is an approximate doubling of the cortisol value.

Performing Laboratory

Asante Rogue Regional Medical Center

 

Performing Department

Chemistry

Specimen Required

(submit one of the following)

Yellow (Gold) top tube (SST)- Outpatient clients MUST draw SST

Lithium Heparin Green top tube

2 Yellow microtainers (outpatients)

2 Green microtainers (inpatients)

Blood may be drawn between:

5:00 and 10:00 A.M. for A.M. draw

After 4:00 P.M. for P.M. draw.

Specimen Minimum Volume

1.0 mL whole blood (for all ages)

Specimen Stability

Centrifuge and refrigerate within 2 hours of collection

Primary tube: Spun SST stable 24 hours at 2° to 8° C

Serum stable 48 hours if aliquoted and refrigerated at 2° to 8° C

Reject Due To

  • Hemolysis
  • Quantity not sufficient (QNS)
  • Lack of Two Patient Identifiers:
    • 1-Patient's First & Last name 
    • 2-Patient's Date of Birth

Day(s) Performed

Monday through Sunday

Turnaround time:

Routine – 4 hour after receipt of specimen in lab

STAT - 1 hour after receipt of specimen in lab

Method Name

Chemiluminescence (CLIA)

CPT Code Information

82533  -  Cortisol; total

Billing Code

2070100