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Test Code LAB549 Hepatitis B Core Antibody - IgM (Anti-HBc-IgM)

Performing Laboratory

Asante Rogue Regional Medical Center

Specimen Minimum Volume

0.5 mL

Billing Code

2071645

Methodology

Chemiluminescence (CLIA)

Specimen Requirements

Yellow (Gold) top tube (SST)

Plain Red top tube  

 

Cord blood is NOT to be used 

Lipemic specimens should be clarified

Day(s) Test Set Up

Tests performed Monday through Friday.

 

Positive results are called to physician

 

Positive results also require public health reporting and follow up

Test Classification and CPT Coding

86705  -  Hepatitis B core antibody (HBcAb); IgM antibody

Additional Information

This is the test for IgM antibody to the Core Antigen of the Hepatitis B Virus.  It is a marker of acute infection and is usually present for up to six  months after exposure.
 

Anti-HBc appears 5-14 days after “e” antigen and can be found shortly before HBsAg is no longer detectable.  The period between the disappearance of HBsAg and the appearance of HBsAb is often called the “core window.” Simultaneous presence of HBc-IgM with Hepatitis B Surface Antigen indicates an acute infection.  A positive HBc-IgM with a negative HBsAg suggests a recent acute infection.  In this case, subsequent testing for Anti-HBs and/or Anti-HBe will help track the progression toward immunity.

Performing Department

Chemistry

Reasons for Rejection

Icterus

Lipemic

Hemolysis

Quantity not sufficient (QNS)

Lack of Two Patient Identifiers:

         1-Patient’s First & Last name 

         2-Patient’s Date of Birth

Specimen Transport Temperature and Stability

Centrifuge and refrigerate within 2 hours of collection

Serum stable 7 days refrigerated at 2° to 8° C

Freeze for longer storage.