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HelpTest Code LAB5357 Porphyrins, Feces
Performing Laboratory
Mayo Clinic Laboratories in Rochester
Reporting Name
Porphyrins, FSpecimen Type
FecalNecessary Information
1. Weight of the non-homogenized sample
2. Collection duration
3. Include a list of medications the patient is currently taking.
4. Indicate if patient was compliant with the patient preparation requirements.
Specimen Required
Patient Preparation:
1. For 3 days before, as well as during, specimen collection, patient must not eat red meat or take any aspirin-containing medications.
2. For 24 hours before, as well as during, specimen collection, patient must not use barium, laxatives, or enemas.
Supplies: Stool Containers - 24, 48, 72 Hour Kit (T291)
Container/Tube: Stool containers
Specimen Volume: Entire collection (48, 72, or 96 hours). 24-Hour collection is adequate if the collection volume is at least 100 g
Collection Instructions:
1. Collect all stool specimens within a 24, 48, 72, or 96-hour timeframe.
2. Do not add preservative.
3. Send entire collection.
Additional Information: Specimens smaller than 100 g may not provide accurate results.
Reject Due To
| Specimens in preservative | Reject |
Specimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Fecal | Frozen (preferred) | 14 days |
| Refrigerated | 14 days |
Specimen Minimum Volume
See Specimen Required
Special Instructions
Day(s) Performed
Monday, Thursday
Specimen Retention Time
1 weekReport Available
3 to 6 daysReference Values
Uroporphyrin I: <120 mcg/24 h
Uroporphyrin III: <50 mcg/24 h
Heptacarboxyl I: <40 mcg/24 h
Heptacarboxyl III: <40 mcg/24 hours
Isoheptacarboxyl: <30 mcg/24 h
Hexacarboxyl I: <10 mcg/24 h
Hexacarboxyl III: <10 mcg/24 h
Isohexacarboxyl: <10 mcg/24 h
Pentacarboxyl I: <20 mcg/24 hours
Pentacarboxyl III: <20 mcg/24 h
Isopentacarboxyl: <80 mcg/24 hours
Coproporphyrin I: <500 mcg/24 h
Coproporphyrin III: <400 mcg/24 h
Isocoproporphyrin: <200 mcg/24 h
Protoporphyrin: <1,500 mcg/24 h
CoproIII/CoproI ratio: <1.20
Useful For
Evaluation of patients who present with signs or symptoms suggestive of porphyria cutanea tarda, hereditary coproporphyria, variegate porphyria, congenital erythropoietic porphyria, erythropoietic protoporphyria, or X-linked protoporphyria
CPT Code Information
84126
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| FQPPS | Porphyrins, F | 94548-5 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| W6 | Total weight | 30078-0 |
| TM70 | Collection Duration | 13363-7 |
| 15517 | Uroporphyrin I | 26691-6 |
| 15518 | Uroporphyrin III | 33585-1 |
| 15519 | Heptacarboxyl I | 49900-4 |
| 15520 | Heptacarboxyl III | 49901-2 |
| 15521 | Isoheptacarboxyl | 94549-3 |
| 15522 | Hexacarboxyl I | 94550-1 |
| 15523 | Hexacarboxyl III | 94551-9 |
| 15524 | Isohexacarboxyl | 94552-7 |
| 15525 | Pentacarboxyl I | 33623-0 |
| 15526 | Pentacarboxyl III | 33624-8 |
| 15527 | Isopentacarboxyl | 94553-5 |
| 15528 | Coproporphyrin I | 23845-1 |
| 15529 | Coproporphyrin III | 23846-9 |
| 15530 | Isocoproporphyrin | 33625-5 |
| 15534 | Protoporphyrin | 2891-0 |
| 15545 | CoproIII/CoproI ratio | 33618-0 |
| 81652 | Interpretation (FQPPS) | 59462-2 |
| 35013 | Reviewed By | 18771-6 |
Method Description
The porphyrins are separated according to numbers of carboxyl units and isomer status. Analytic specificity is based on the combination of chromatographic behavior and the uniqueness of the porphyrins among substances in human specimens in terms of fluorescence spectra. Components quantified are 10 specific porphyrins of isomer series I and III, 4 groups of isoporphyrins (isomers other than series I and III), and protoporphyrin.(Unpublished Mayo method)
Disease States
- Porphyria
Forms
If not ordering electronically, complete, print, and send a Biochemical Genetics Test Request (T798) with the specimen.