Test Code LAB5310 Antineutrophil Cytoplasmic Antibodies Vasculitis Panel, Serum
Performing Laboratory
Mayo Clinic Laboratories in RochesterReporting Name
ANCA Panel for Vasculitis, SSpecimen Type
SerumOrdering Guidance
For monitoring disease activity, order either PR3 / Proteinase 3 Antibodies, IgG, Serum or MPO / Myeloperoxidase Antibodies, IgG, Serum.
Specimen Required
Supplies: Sarstedt Aliquot Tube 5 mL (T914)
Collection Container/Tube:
Preferred: Serum gel
Acceptable: Red top
Submission Container/Tube: Plastic vial
Specimen Volume: 1 mL
Collection Instructions: Centrifuge and aliquot serum into a plastic vial.
Reject Due To
Gross hemolysis | Reject |
Gross lipemia | Reject |
Gross icterus | OK |
Specimen Stability Information
Specimen Type | Temperature | Time | Special Container |
---|---|---|---|
Serum | Refrigerated (preferred) | 21 days | |
Frozen | 21 days |
Specimen Minimum Volume
0.5 mL
Day(s) Performed
Monday through Saturday
Specimen Retention Time
14 daysReport Available
3 to 4 daysReference Values
MYELOPEROXIDASE ANTIBODIES, IgG
<0.4 U (negative)
0.4-0.9 U (equivocal)
≥1.0 U (positive)
Reference values apply to all ages.
PROTEINASE 3 ANTIBODIES, IgG
<0.4 U (negative)
0.4-0.9 U (equivocal)
≥1.0 U (positive)
Reference values apply to all ages.
Reflex Tests
Test ID | Reporting Name | Available Separately | Always Performed |
---|---|---|---|
ANCA | Cytoplasmic Neutrophilic Ab, S | Yes | No |
Useful For
Evaluating patients with clinical features of anti-neutrophil cytoplasmic antibody-associated vasculitis, specifically granulomatosis with polyangiitis, microscopic polyangiitis, and eosinophilic granulomatosis with polyangiitis
Testing Algorithm
If either the myeloperoxidase antibody or proteinase 3 antibody result is greater than or equal to 0.4 U, then cytoplasmic neutrophilic antibody testing will be performed at an additional charge.
CPT Code Information
83516 x 2
86036 x 2 (if appropriate)
LOINC Code Information
Test ID | Test Order Name | Order LOINC Value |
---|---|---|
VASC | ANCA Panel for Vasculitis, S | 90230-4 |
Result ID | Test Result Name | Result LOINC Value |
---|---|---|
MPO | Myeloperoxidase Ab, S | 48404-8 |
PR3 | Proteinase 3 Ab (PR3), S | 74106-6 |
Profile Information
Test ID | Reporting Name | Available Separately | Always Performed |
---|---|---|---|
MPO | Myeloperoxidase Ab, S | Yes | Yes |
PR3 | Proteinase 3 Ab (PR3), S | Yes | Yes |
Forms
If not ordering electronically, complete, print, and send 1 of the following forms with the specimen:
-General Request (T239)
-Renal Diagnostics Test Request (T830)