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HelpTest Code LAB5180 Tobramycin, Timed
Useful For
There are three options for ordering Tobramycin levels:
TOBPST (post dose), TOBPRE (pre or trough dose) and TOBTIM (extended interval dosing, 12 hours from
beginning of IV infusion). Generally, the TOBTIM sample may be drawn as early as 10 hours from
the start of the infusion. The exact timed request from pharmacy/nursing must be observed.
These requests should not be “bumped” to a more convenient draw time.
Use: Tobramycin is an aminoglycoside
antibiotic whose activity is similar to that of Gentamicin against
gram negative bacteria. Tobramycin exhibits a narrow
therapeutic range which makes its use hazardous, especially in
patients with impaired renal function.
Performing Laboratory
Asante Three Rivers Medical Center (ATRMC)
Performing Department
Chemistry
Specimen Required
RRMC:
Lithium Heparin Green top tube
Outpatient clients MUST draw SST
TRMC:
Plain Red top tube No SST or PST
Consult with RRMC pharmacy.
Draw 12 hours after the start of infusion of dose. See Additional Information section.
RRMC Outpatient clients must draw SST,
Limited stability with PST
Specimen Minimum Volume
0.5 mL
Specimen Stability Information
RRMC:
Centrifuge collection tube within 2 hours of collection
Stable 8 hours at room temperature
Serum stable 48 hours if aliquoted and refrigerated at 2° to 8° C
TRCH:
Centrifuge collection tube and refrigerate within 2 hours of collection
Serum stable for 48 hours at 2° to 8° C
Reject Due To
Icterus
Lipemia
Hemolysis
Quantity not sufficient (QNS)
Lack of Two Patient Identifiers:
1-Patient's First & Last name
2-Patient's Date of Birth
Day(s) Performed
Routine - same day;
ASAP - 2 hours after receipt of specimen in laboratory;
STAT - 1 hour after receipt of specimen in laboratory.
Method Name
Turbidimetric Inhibition
CPT Code Information
80200 Tobramycin – Therapeutic Drug Assay
Billing Code
80200 Tobramycin – Therapeutic Drug Assay