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HelpTest Code LAB5164 Protoporphyrins, Fractionation, Whole Blood
Performing Laboratory
Mayo Clinic Laboratories in Rochester
Reporting Name
Protoporphyrins, Fractionation, WBSpecimen Type
Whole bloodOrdering Guidance
This test is for assessment for protoporphyria. The preferred test for lead toxicity in children is blood lead. For more information see PBDV / Lead, Venous with Demographics, Blood or PBDC / Lead, Capillary, with Demographics, Blood. The preferred screening test for suspicion of a hepatic porphyria is urine porphyrins. For more information see PQNRU / Porphyrins, Quantitative, Random, Urine. This test should not be ordered with PEE / Porphyrins Evaluation, Whole Blood
Necessary Information
Include a list of medications the patient is currently taking.
Specimen Required
All porphyrin tests on whole blood can be performed on 1 tube.
Patient Preparation: Patient must not consume any alcohol for 24 hours before specimen collection.
Container/Tube:
Preferred: Green top (sodium heparin)
Acceptable: Dark blue top (metal free heparin), green top (lithium heparin), or lavender top (EDTA)
Specimen Volume: 4 mL
Collection Instructions: Refrigerate specimen as soon as possible.
Reject Due To
| Gross hemolysis | Reject |
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Whole blood | Refrigerated | 7 days |
Specimen Minimum Volume
3 mL
Special Instructions
Day(s) Performed
Monday through Friday
Specimen Retention Time
14 daysReport Available
3 to 5 daysReference Values
FREE PROTOPORPHYRIN
<20 mcg/dL
ZINC-COMPLEXED PROTOPORPHYRIN
<60 mcg/dL
Useful For
Evaluating patients with possible diagnoses of erythropoietic protoporphyria or X-linked dominant protoporphyria
Establishing a biochemical diagnosis of erythropoietic protoporphyria and X-linked dominant protoporphyria
Testing Algorithm
This test should not be ordered in conjunction with PEE / Porphyrins Evaluation, Whole Blood.
The following information is available:
-Porphyria (Acute) Testing Algorithm
CPT Code Information
82542
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| PPFE | Protoporphyrins, Fractionation, WB | 94490-0 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| 2327 | Zinc-Complexed Protoporphyrin | 2895-1 |
| 2326 | Free Protoporphyrin | 94491-8 |
| 29511 | Interpretation | 59462-2 |
Forms
If not ordering electronically, complete, print, and send a Biochemical Genetics Test Request (T798) with the specimen.