Home
HelpTest Code LAB466 Clonazepam and 7-Aminoclonazepam, Serum
Test Down Notes
This test is temporarily unavailable due to instrumentation issues. As an alternate, order FCLMS. For additional details, see test update here.
Useful For
Assessing patient compliance
Monitoring for appropriate therapeutic level
Assessing clonazepam toxicity
Reporting Name
Clonazepam and 7-Aminoclonazepam, SSpecimen Type
Serum RedSpecimen Required
Collection Container/Tube: Red top
Submission Container/Tube: Plastic vial
Specimen Volume: 1.2 mL
Collection Instructions:
1. Draw blood immediately before next scheduled dose (minimum 12 hours after last dose).
2. Within 2 hours of collection, the specimen must be centrifuged and the serum aliquoted into a plastic vial.
Specimen Minimum Volume
0.6 mL
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Serum Red | Refrigerated (preferred) | 14 days | |
| Frozen | 28 days | ||
| Ambient | 72 hours |
Reject Due To
| Gross hemolysis | OK |
| Gross lipemia | OK |
| Gross icterus | Reject |
Reference Values
Clonazepam
Anticonvulsant: 20-70 ng/mL
Anxiolytic: 4-80 ng/mL
Some individuals may show therapeutic response outside of these ranges or may display toxicity within the therapeutic range, thus interpretation should include clinical evaluation.
Note: Therapeutic ranges are for specimens collected at trough (ie, immediately before next scheduled dose). Levels may be elevated in non-trough specimens.
Day(s) Performed
Monday, Wednesday
Report Available
3 to 7 daysSpecimen Retention Time
14 daysPerforming Laboratory
Mayo Clinic Laboratories in Rochester
CPT Code Information
80299
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| CZPS | Clonazepam and 7-Aminoclonazepam, S | 104541-8 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| 65044 | Clonazepam | 3494-2 |
| 41782 | 7-Aminoclonazepam | 28059-4 |
Forms
If not ordering electronically, complete, print, and send a Therapeutics Test Request (T831) with the specimen.