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Test Code LAB464 Phospholipid (Cardiolipin) Antibodies, IgG and IgM, Serum

Important Note

Mayo test code: CLPMG

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Reporting Name

Phospholip Ab (Cardiolip) IgM/IgG

Specimen Type

Serum


Specimen Required


Supplies: Sarstedt Aliquot Tube, 5 mL (T914)

Collection Container/Tube:

Preferred: Serum gel

Acceptable: Red top

Submission Container/Tube: Plastic vial

Specimen Volume: 0.5 mL

Collection Instructions: Centrifuge and aliquot serum into a plastic vial.


Reject Due To

Gross hemolysis Reject
Gross lipemia Reject
Gross icterus OK
Heat-treated specimen Reject

Specimen Stability Information

Specimen Type Temperature Time Special Container
Serum Refrigerated (preferred) 21 days
  Frozen  21 days

Specimen Minimum Volume

0.4 mL

Day(s) Performed

Monday through Saturday

Specimen Retention Time

14 days

Report Available

Same day/1 to 2 days

Reference Values

MPL refers to IgM phospholipid units. One MPL unit is 1 microgram of IgM antibody.

GPL refers to IgG phospholipid units. One GPL unit is 1 microgram of IgG antibody.

 

Negative: <15.0 MPL or GPL

Weakly positive: 15.0-39.9 MPL or GPL

Positive: 40.0-79.9 MPL or GPL

Strongly positive: ≥80.0 MPL or GPL

 

Reference values apply to all ages.

Useful For

The following clinical situations:

-Unexplained arterial or venous thrombosis

-A history of pregnancy morbidity defined as 1 or more unexplained deaths of a morphologically normal fetus beyond the 10th week of gestation, 1 or more premature births before 34 weeks of gestation caused by severe preeclampsia or placental insufficiency, or 3 or more unexplained, consecutive spontaneous abortions before the 10th week of gestation with no identifiable maternal hormonal or anatomic, or maternal or paternal chromosomal causes

-Presence of a systemic autoimmune rheumatic disease especially systemic lupus erythematosus

-Presence of an unexplained cutaneous manifestations varying from livedo reticularis to cutaneous necrosis such as leg ulcers

-Unexplained thrombocytopenia

-Possible nonbacterial, thrombotic endocarditis

CPT Code Information

86147 x 2

LOINC Code Information

Test ID Test Order Name Order LOINC Value
CLPMG Phospholip Ab (Cardiolip) IgM/IgG 24319-6

 

Result ID Test Result Name Result LOINC Value
GCLIP Phospholipid Ab IgG, S 3181-5
MCLIP Phospholipid Ab IgM, S 3182-3

Profile Information

Test ID Reporting Name Available Separately Always Performed
MCLIP Phospholipid Ab IgM, S Yes Yes
GCLIP Phospholipid Ab IgG, S Yes Yes

Forms

If not ordering electronically, complete, print, and send 1 of the following forms with the specimen:

-Coagulation Test Request (T753)

-Renal Diagnostics Test Request (T830)