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Test Code LAB456 Beta Hydroxybutyrate

Useful For

Ketosis is a common feature in acutely ill patients.  In subjects suffering from starvation, acute alcohol abuse, or diabetes mellitus, ketosis can result in severe life-threatening metabolic acidosis.  The presence and degree of ketosis can be determined by measuring blood levels of β-hydroxybutyrate.

Ordinarily, β-hydroxybutyrate is the ketoacid present in the greatest amount in serum.  It accounts for approximately 75% of the ketone bodies which also contain acetoacetate and acetone.  During periods of ketosis, β-hydroxybutyrate increases even more than the other two ketoacids, acetoacetate and acetone, and has been shown to be a better index of ketoacidosis including the detection of subclinical ketosis.

In diabetics, the measurement of β-hydroxybutyrate as well as the blood glucose is needed for the assessment of the severity of diabetic coma, and both are essential for the exclusion of hyperosmolar non-ketonic diabetic coma.

Performing Laboratory

Asante Rogue Regional Medical Center (ARRMC)/ Asante Three Rivers Medical Center (ATRMC)

 

Performing Department

Chemistry

Specimen Required

Yellow (Gold) top tube (SST)

Lithium Heparin Green top tube

Plain Red top tube

 

Outpatient clients MUST draw SST

Specimen Minimum Volume

1.0 mL

Specimen Stability Information

Serum or plasma β-hydroxybutyrate levels are stable at least one week if kept tightly capped and refrigerated at 2 to 8° C.

Reject Due To

Hemolysis

Quantity not sufficient (QNS)

Lack of Two Patient Identifiers:

         1-Patient's First & Last name 

         2-Patient's Date of Birth

Day(s) Performed

Monday through Sunday

Routine - same day

ASAP - 2 hours after receipt of specimen in lab

STAT - 1 hour after receipt of specimen in lab

Method Name

Stanbio Method, Enzymatic quantitation of β-hydroxybutyrate

CPT Code Information

82010 Ketone body(s) (eg, acetone, acetoacetic acid, beta-hydroxybutyrate); quantitative

Billing Code

3010204