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General Information

Mayo Clinic Laboratories

Test Code LAB36 Tobramycin, Post/Peak

Performing Laboratory

Asante Three Rivers Medical Center

Specimen Minimum Volume

0.5 mL

Billing Code

2051233

Methodology

Turbidimetric Inhibition

Specimen Requirements

RRMC:

Yellow (Gold) top tube (SST)

Plain Red top tube

Lithium Heparin Green top tube

 

Specimen should be collected at the completion of a 60-minute infusion

Pre and post labeling of samples is critical

Outpatient clients MUST draw SST

 

TRMC:  

Plain Red top tube  No SST or PST

 

Specimen should be collected at the completion of a 60-minute infusion

Pre and post labeling of samples is critical

Reasons for Rejection

Icterus

Lipemia

Hemolysis

Quantity not sufficient (QNS)

Lack of Two Patient Identifiers:

         1-Patient's First & Last name 

         2-Patient's Date of Birth   

Day(s) Test Set Up

Routine – same day

ASAP – 2 hours after receipt of specimen in lab

STAT – 1 hour after receipt of specimen in lab

Test Classification and CPT Coding

80200  -  Tobramycin, Therapeutic Drug Assay

Additional Information

Tobramycin is an aminoglycoside antibiotic whose activity is similar to that of Gentamicin against gram negative bacteria.  Tobramycin exhibits a narrow therapeutic range which makes its use hazardous, especially in patients with impaired renal functions.

Specimen Transport Temperature and Stability

RRMC:

Centrifuge collection tube within 2 hours of collection

Stable 8 hours at room temperature

Serum stable 48 hours if aliquoted and refrigerated at 2° to 8° C

 

TRCH:

Centrifuge collection tube and refrigerate within 2 hours of collection

Serum stable for 48 hours at 2° to 8° C  

Performing Department

Chemistry