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HelpTest Code LAB23 Digoxin
Useful For
Digoxin is a potent cardiac glycoside, isolated from the leaves of Digitalis lanata, widely prescribed for treatment of congestive heart failure, atrial fibrillation, tachycardia and other cardiac disorders. The clinical use of digoxin is complicated by a high incidence of toxicity. Since digoxin has a very narrow therapeutic range, the measurement of serum digoxin levels provides useful information in the management if digitalized patients.
RRMC
Therapeutic Range (Heart Failure): 0.5-0.9 ng/mL
To obtain steady-state serum digoxin concentrations, blood samples should be drawn 6-8 hours after the daily dose or just prior to the next scheduled dose.
Considerable intra-individual variations exist in the relationship between digoxin serum concentrations and the dosage administered. In addition, the therapeutic range is narrow and varies from individual to individual. Other factors such as age, general condition, cardiovascular status, and renal function also influence the appropriate therapeutic dose
Performing Laboratory
- Asante Rogue Regional Medical Center
- Asante Three Rivers Medical Center
- Asante Ashland Community Hospital
Performing Department
Chemistry
Specimen Required
RRMC and AACH:
Draw blood 6 to 8 hours after last oral dose, please provide last dose information
TRMC:
Draw blood 6 to 8 hours after last oral dose, please provide last dose information
Specimen Minimum Volume
0.5 mL
Specimen Stability Information
Centrifuge and refrigerate within 2 hours of collection
Primary tube: Spun SST is stable for 24 hours if refrigerated at 2° to 8° C
Serum stable 48 hours if aliquoted and refrigerated at 2° to 8° C
Reject Due To
Hemolysis
Quantity not sufficient (QNS)
Lack of Two Patient Identifiers:
1-Patient's First & Last name
2-Patient's Date of Birth
Day(s) Performed
Routine – same day - Run daily 24/7
ASAP – 2 hours after receipt of specimen in lab
STAT – 1 hour after receipt of specimen in lab
Method Name
Chemiluminescence - RRMC and AACH
Turbidimetric Inhibition - TRMC
CPT Code Information
80162 - Digoxin
Billing Code
2070134
Secondary ID
Lanoxin (Digoxin)