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Test Code LAB207 VDRL, Spinal Fluid

Important Note

Mayo code is VDSF

ASANTE order code: CVDRL

 

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Reporting Name

VDRL, CSF

Specimen Type

CSF


Ordering Guidance


For assessment of intrathecally synthesized Treponema pallidum antibodies in spinal fluid (CSF) (ie, the method corrects for any passive diffusion of antibodies from serum into the CSF), order NSAIP / Neurosyphilis IgG Antibody Index with VDRL, Serum and Spinal Fluid.



Specimen Required


Collection Container/Tube: Sterile vial

Submission Container/Tube: Plastic vial

Specimen Volume: 0.5 mL

Collection Instructions: Submit specimen collected in vial 2, if possible. If not, note from which vial the aliquot was obtained.


Reject Due To

Gross hemolysis Reject
Gross lipemia Reject

Specimen Stability Information

Specimen Type Temperature Time
CSF Frozen (preferred) 14 days
  Refrigerated  14 days

Specimen Minimum Volume

0.2 mL

Day(s) Performed

Monday through Friday

Specimen Retention Time

14 days

Report Available

1 to 4 days

Reference Values

Negative

Reference values apply to all ages.

Reflex Tests

Test ID Reporting Name Available Separately Always Performed
VDSFQ VDRL Titer, CSF No No

Useful For

Aiding in the diagnosis of neurosyphilis

Testing Algorithm

If this test is positive, a VDRL titer will be performed at an additional charge.

CPT Code Information

86592

LOINC Code Information

Test ID Test Order Name Order LOINC Value
VDSF VDRL, CSF 5290-2

 

Result ID Test Result Name Result LOINC Value
9028 VDRL, CSF 5290-2

Method Description

The VDRL antigen and spinal fluid are mixed on a 180 RPM rotator. The antigen, a cardiolipin-lecithin coated cholesterol particle, flocculates in the presence of reagin.(US Department of Health, Education and Welfare, National Communicable Diseases Center, Venereal Disease Program: Manual of Tests for Syphilis. Centers for Disease Control; 1969; Bennett JE, Dolin R, Blaser MJ, eds. Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases. 9th ed. Elsevier; 2020)