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Test Code LAB171 Prostate Specific Antigen (PSA), Total PSA and Free PSA

Performing Laboratory

Asante Rogue Regional Medical Center

Specimen Minimum Volume

0.5 mL

Billing Code

3010552 Prostate specific antigen (PSA); total

3010195  Prostate specific antigen (PSA); free

Methodology

Chemiluminescence (CLIA)

Specimen Requirements

Yellow (Gold) top tube (SST)

 

Manipulation of prostate may increase values
Collect before digital rectal examination, prostatic massage, or transurethral ultrasound

Day(s) Test Set Up

Monday through Sunday

Test Classification and CPT Coding

84154 Prostate specific antigen (PSA); free

84153 Prostate specific antigen (PSA); total

Additional Information

PSA exists in two forms: 

  • PSA bound to alpha-1 antichymotrypsin and alpha-2 macroglobin as well as the “free” form (Free PSA). 
  • Patients with total (bound and free) PSA in the 4-10 ng/mL range who have a non-suspicious digital rectal exam may benefit from a % free PSA as the lower the percent free PSA is, the higher the risk of prostate cancer. 

 

To determine % free PSA, both a total PSA and a free PSA must be run concurrently.

Performing Department

Chemistry

Reasons for Rejection

Hemolysis

Quantity not sufficient (QNS)

Lack of Two Patient Identifiers:

         1-Patient’s First & Last name 

         2-Patient’s Date of Birth

Specimen Transport Temperature and Stability

Centrifuge, aliquot and refrigerate within 2 hours of collection

Freeze serum if testing is delayed beyond 24 hours