Sign in →

Test Code LAB1235218 Hepatitis B Core Total Antibody

Performing Laboratory

Asante Rogue Regional Medical Center

Specimen Minimum Volume

0.75 mL

Billing Code

3020048

Specimen Requirements

Yellow (Gold) top tube (SST)

Plain Red top tube

Specimen Transport Temperature and Stability

Centrifuge and refrigerate within 2 hours of collection

Serum stable 4 days refrigerated at 2° to 8° C

Freeze for longer storage

Reasons for Rejection

Icterus

Lipemia

Hemolysis

Quantity not sufficient (QNS)

Lack of Two Patient Identifiers:

         1-Patient’s First & Last name 

         2-Patient’s Date of Birth

Day(s) Test Set Up

Tests are performed Monday through Friday.

Positive results are called to physician

Positive results also require public health reporting and follow-up

Additional Information

Hepatitis B core antibodies (anti-HBc Ab) appear shortly after the onset of symptoms of hepatitis B infection and soon after the appearance of hepatitis B surface antigen (HBsAg). Initially, anti-HBc Ab consist almost entirely of the IgM class, followed by appearance of anti-HBc IgG, for which there is no commercial diagnostic assay.

 

The anti-HBc total antibodies test, which detects both IgM and IgG antibodies, and the test for anti-HBc IgM antibodies may be the only markers of a recent hepatitis B infection detectable in the "window period." The window period begins with the clearance of HBsAg and ends with the appearance of antibodies to hepatitis B surface antigen (anti-HBs Ab). Anti-HBc total Ab may be the only serologic marker remaining years after exposure to hepatitis B.

Methodology

Chemiluminescence (CLIA)

Performing Department

Chemistry

Test Classification and CPT Coding

86704